Sort   by:  
 Page size 
MetabolomicsA Pathogen-Responsive Gene Cluster for Highly Modified Fatty Acids in Tomato
In response to biotic stress, plants produce suites of highly modified fatty acids that bear unusual chemical functionalities. Despite their chemical complexity and proposed roles in pathogen defense, little is known about the biosynthesis of decorated fatty acids in plants. Falcarindiol is a protot...
2022-01-17 | MTBLS1039 | MetaboLights
UnknownLongitudinal changes in ventricular function and atrioventricular valve failure following cardiac morphology after Fontan procedure.

Background

Ventricular dysfunction and atrioventricular valve (AVV) failure in Fontan patients are associated with adverse long-term outcomes; however, data on longitudinal changes and their relationship with morphology are lacking. This study aimed to describe longitudinal changes in ventri...
S-EPMC12268634 | biostudies-literature
Genomicswhole exome sequencing of Korean hepatocellular carcinomas
Data Access Committee EGAC00001000329
EGAC00001000329 | EGA
TranscriptomicsGenome-wide expression profiling in a Fusarium graminearum lacking FgVelB, a velvet complex gene
Using a 3'-tiling microarray covering the whole F. graminearum genes, we carried out genome-wide expression analyses of both a wild type and a FgVelB deletion strainn of F. graminearum at a sexual stage (3 days after perithecial induction on carrot agar) Our study is the first report elucidating re...
ORGANISM(S): Gibberella zeae 
2012-08-02 | E-GEOD-36638 | biostudies-arrayexpress
UnknownIdentification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers.

Background

Lung adenocarcinoma is a highly heterogeneous disease with various etiologies, prognoses, and responses to therapy. Although genome-scale characterization of lung adenocarcinoma has been performed, a comprehensive somatic mutation analysis of EGFR/KRAS/ALK-negative lung adenocarci...
S-EPMC3979047 | biostudies-literature
UnknownSerum Extracellular Vesicle-Associated GULP1 Is a Key Indicator of Hepatocellular Carcinoma.

Objectives

Early detection of hepatocellular carcinoma (HCC) is a significant challenge due to the limited sensitivity of alpha-fetoprotein (AFP). This study aimed to assess serum-derived extracellular vesicle-encapsulated GULP PTB domain-containing engulfment adaptor 1 (EV-GULP1) as ...
S-EPMC12848681 | biostudies-literature
UnknownClinical importance of weight gain and associated factors in patients with moderate to severe ulcerative colitis: results from the MOSAIK cohort in Korea.

Background

Many patients with ulcerative colitis (UC) gain weight after treatment. However, the clinical significance of weight gain in these patients remains unclear. This study aimed to evaluate body weight changes after treatment in patients newly diagnosed with moderate-to-severe UC and ...
S-EPMC10664292 | biostudies-literature
UnknownClinical Features and Outcomes of Tuberculosis in Inflammatory Bowel Disease Patients Treated with Anti-tumor Necrosis Factor Therapy.

Background/aims

Anti-tumor necrosis factor (TNF) therapy is used widely for the treatment of inflammatory bowel disease (IBD). In the present study, the characteristics and outcomes of tuberculosis (TB) in IBD patients treated with anti-TNF therapy were compared with those of non-IBD TB pati...
S-EPMC12285826 | biostudies-literature
UnknownBacteroides eggerthii ameliorates metabolic dysfunction-associated steatotic liver disease through host-microbe signaling and highlights 2-hydroxyisocaproate as a potential effector.

Background/aims

Gut microbiome plays a pivotal role in metabolic dysfunction-associated steatotic liver disease (MASLD) pathogenesis, yet, associated functional mechanisms and host responses of specific microbial species remain insufficiently characterized. This study investigated the Bacter...
S-EPMC12835788 | biostudies-literature
UnknownMechanistic Investigation of WWOX Function in NF-kB-Induced Skin Inflammation in Psoriasis.
Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation, aberrant differentiation of keratinocytes, and dysregulated immune responses. WW domain-containing oxidoreductase (WWOX) is a non-classical tumor suppressor gene that regulates multiple cellular processes...
S-EPMC10779412 | biostudies-literature
Sort   by:  
 Page size