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ProteomicsLysine acetylation of the housekeeping sigma factor enhances the activity of RNA polymerase holoenzyme
Protein lysine acetylation is one of the abundant post-translational modifications in eukaryotes, but found in prokaryotes as well. Despite the evidence of the lysine acetylation in the prokaryotic RNA polymerases (RNAPs), its function remains unrevealed. We revealed that the housekeeping sigma fact...
ORGANISM(S): Streptomyces venezuelae 
2020-05-27 | PXD015174 | Pride
Sigma factor Lysine acetylation Rna polymerase Transcription 
ProteomicsWblC- and tetracycline-dependent shifts in the composition of Streptomyces coelicolor ribosomal proteome
WblC, also known as WhiB7, is a widely conserved WhiB-like transcription factor in actinomycetes that activates transcription of many targets upon antibiotic challenge to bring about intrinsic resistance to a wide range of translation-targeting antibiotics. As we found that WblC controls many genes ...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2020-05-27 | PXD015538 | Pride
Streptomyces coelicolor Ribosome Whib7 Wblc Antibiotic stress 
Genomicswhole exome sequencing of Korean hepatocellular carcinomas
Data Access Committee EGAC00001000329
EGAC00001000329 | EGA
TranscriptomicsStreptomyces coelicolor A3(2) SigR regulon
We determined the genomic locations of the SigR binding sites by chromatin immuno-precipitation of cross-linked DNA and hybridization on a tilling oligonucleotide array after 20 minutes of diamide treatment on cell cultures. Three independent biological samples were prepared separately from the wild...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2012-06-02 | E-GEOD-33593 | biostudies-arrayexpress
MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
Genomicsena-DATASET-asan-ccgd-27-09-2019-00:22:21:191-59 - samples
231 HCC exome sequencing with Sureselect 50Mb
EGAD00001005361 | EGA
GenomicsThese are from Korean HCC samples with exome sequencing
Hepatic resection is the most curative treatment option for early-stage hepatocellular carcinoma, but is associated with a high recurrence rate, which exceeds 50% at 5 years after surgery. Understanding the genetic basis of hepatocellular carcinoma at surgically curable stages may enable the identif...
EGAS00001000604 | EGA
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