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UnknownIntegrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.
Not available
S-EPMC4062710 | biostudies-literature
TranscriptomicsGenome-Wide Molecular Signature of Cholangiocarcinoma and Its Trandifferentation-Related Genes
Cholangiocarcinoma (CC) is an aggressive tumor that shows a poor survival rate even after resection. The present study aimed at identification of the genome-wide expressed genes related to CC oncogenesis and its sarcomatous transdifferentiation using DNA microarray technology. The differentially exp...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-22633 | biostudies-arrayexpress
ProteomicsIdentification of DX2 ubiquitination site
Although ubiquitination of DX2, novel oncogene, is significant on its protein stability, but DX2 ubiquitination sites are not unveiled. In this study, we identified ubiquitination sites of DX2 upon treatment with DX2 protein inhibitor, SDL01, via LC-MSMS technique. Lysine 90 of DX2 was revealed as a...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD051772 | Pride
Human Dx2 Uniqutination Cancer cell Lc-ms/ms 
TranscriptomicsGene expression study for effectiveness of nicotinamide using chemically-induced mouse bladder cancer model
The objective of this study was to evaluate the efficacy of nicotinamide in a N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN)-induced urinary bladder cancer model in mice, and to identify through gene expression profiling the molecular signatures of cancer prevention by nicotinamide. We used 20 mice fo...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-21636 | biostudies-arrayexpress
TranscriptomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cells (Methylation BeadChip)
DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge about the genome-wide distribution of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) during cellular differentiation remains limited. Using in vitro model system of gra...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38216 | biostudies-arrayexpress
GenomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cell (hMeDIP-Seq and MBD-Seq)
DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge about the genome-wide distribution of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) during cellular differentiation remains limited. Using in vitro model system of gra...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38214 | biostudies-arrayexpress
TranscriptomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38217 | biostudies-arrayexpress
ProteomicsProteomic signatures of Psychosocial Stress and Western Diet- driven Mitochondrial Dysfunction in Frontal Cortex and Hippocampus
Chronic Stress and Western diet are major risk factors for affective disorders, however their biological interactions remain unclear. This study examined the neurochemical, mitochondrial, metabolic, behavioural and proteomic effects of a chronic stress paradigm (2h/day for 2 weeks) in male C57bl/6 m...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD074187 | Pride
Depression Mitochondria Stress Mouse Respiration Synaptogenesis Anxiety Western diet Co-morbidity 
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
TranscriptomicsExpression data from porcine embryonic stem cells
We have been able to derive EpiSC-like pESC lines from in vivo produced porcine blastocysts. Our cell lines showed AP activity, expressions of the genes Oct4, Sox2, Nanog, Rex1, TDGF1, bFGF, FGFR1, FGFR2, Nodal and Activin-A involved in pluripotency and signaling pathways and in vitro differentiatio...
ORGANISM(S): Sus scrofa 
2011-12-31 | E-GEOD-32506 | biostudies-arrayexpress
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