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UnknownCholesterol inhibits M-type K+ channels via protein kinase C-dependent phosphorylation in sympathetic neurons.
Not available
S-EPMC2856299 | biostudies-literature
UnknownA randomized phase 1 study of safety, tolerability, and pharmacokinetics of MK-1088, a novel dual adenosine receptor antagonist, in healthy adult participants.
Not available
S-EPMC11625052 | biostudies-literature
MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
UnknownCD82 controls CpG-dependent TLR9 signaling.
Not available
S-EPMC6988855 | biostudies-literature
UnknownHistone Lys demethylase KDM3C demonstrates anti-inflammatory effects by suppressing NF-κB signaling and osteoclastogenesis.
Not available
S-EPMC6704463 | biostudies-literature
ProteomicsHIF Regulates Multiple Translated Endogenous Retroviruses: Implications for Cancer Immunotherapy
Jiang Q, Braun DA, Clauser KR, Ramesh V, Shirole NH, Duke-Cohan JE, Nabilsi N, Karmer NJ, Forman C, Lippincott IE, Klaeger S, Phulphagar KM, Chea V, Kim N, Vanasse AP, Saad E, Parsons T, Carr-Reynolds M, Carulli I, Pinjusic K, Jiang Y, Li R, Syamala S, Rachimi S, Verzani EK, Stevens JD, Lane WJ, Cam...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-13 | MSV000096406 | MassIVE
UnknownChromosome-encoded AmpC and CTX-M extended-spectrum β-lactamases in clinical isolates of Proteus mirabilis from Korea.
Not available
S-EPMC3067170 | biostudies-literature
ProteomicsNSMF promotes the replication stress-induced DNA damage response for genome maintenance
Proper activation of DNA repair pathways in response to DNA replication stress is critical for maintaining genomic integrity. Due to the complex nature of the replication fork (RF), problems at the RF require multiple proteins, which remain unidentified, for resolution. In this study, we identified ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021942 | Pride
Atr Cdc5l Rpa2 Replication fork Lc-ms/ms 
ProteomicsAlteration in Tyrosine Phosphorylation of Cardiac Proteome and EGFR Pathway Contribute to Hypertrophic Cardiomyopathy
Alterations of serine/threonine phosphorylation of the cardiac proteome are a hallmark of heart failure. However, the contribution of tyrosine phosphorylation (pTyr) to the pathogenesis of cardiac hypertrophy remains unclear. We use global mapping to discover and quantify site-specific pTyr in two c...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD036506 | Pride
Heart Tyrosine phosphorylation Proteomics Serine phosphorylation Threonine phosphorylation 
UnknownContemporary Statistics of Acute Ischemic Stroke and Transient Ischemic Attack in 2021: Insights From the CRCS-K-NIH Registry.
Not available
S-EPMC11372415 | biostudies-literature
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