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ProteomicsMetabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis
A hallmark of cancer cells is the metabolic switch from oxidative phosphorylation (OXPHOS) to glycolysis, a phenomenon referred to as the “Warburg effect”, which is also observed in primed human pluripotent stem cells (hPSCs). Here, we report that downregulation of SIRT2 and upregulation of SIRT1 is...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD006036 | Pride
Acetylation Sirt2 Differentiation Human pluripotent stem cells 
UnknownBiotransformation of 2-keto-4-hydroxybutyrate via aldol condensation using an efficient and thermostable carboligase from Deinococcus radiodurans.
Not available
S-EPMC10992282 | biostudies-literature
ProteomicsPlatycodi Radix Extract Prevents Hepatic Steatosis by Enhancing Bile Acid Synthesis in a High-Fat Diet-Induced Fatty Liver Mouse Model
This project investigated the molecular mechanism by which *Platycodi Radix* extract (PRE; the ethanol extract of the root of *Platycodon grandiflorum*) prevents non-alcoholic fatty liver disease (NAFLD) in a high-fat diet (HFD)-induced fatty liver mouse model, using a liver-tissue shotgun proteomic...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-04 | PXD080181 | Pride
Platycodon radix Proteomics Obesity Nafld 
UnknownUSP15 negatively regulates lung cancer progression through the TRAF6-BECN1 signaling axis for autophagy induction.
Not available
S-EPMC9010460 | biostudies-literature
UnknownSustainable Bioconversion of Methanol: A Renewable Employing Novel Alcohol Oxidase and Pyruvate Aldolase.
Not available
S-EPMC12007092 | biostudies-literature
UnknownPreexisting comorbidities are associated with the mortality rate as well as the predialysis adverse events in incident dialysis patients.
Not available
S-EPMC8476300 | biostudies-literature
UnknownEffects of decitabine on allogeneic immune reactions of donor lymphocyte infusion via activation of dendritic cells.
Not available
S-EPMC7470611 | biostudies-literature
UnknownLycopene enhances epigenetic reprogramming and zygotic genome activation in the porcine somatic cell nuclear transfer embryo.
Not available
S-EPMC12475035 | biostudies-literature
UnknownSurgically resected T1- and T2-stage esophageal squamous cell carcinoma: T and N staging performance of EUS and PET/CT.
Not available
S-EPMC6089181 | biostudies-literature
UnknownEfficient Plant Regeneration System from Leaf Explant Cultures of Daphne genkwa via Somatic Embryogenesis.
Not available
S-EPMC10255457 | biostudies-literature
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