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ProteomicsProteogenomic characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling
Hyperactivated mTOR signaling in the developing brain by mutation of TSC1 genes has multiple forms of pathology including tuberous sclerosis complex (TSC). To examine the downstream networks affected in the developing brain by hyperactivated mTOR signaling, we performed an integrated analysis of tra...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-16 | PXD005768 | Pride
Lc-msms Mouse Brain Forebrain 
UnknownAntisense-oligonucleotide co-micelles with tumor targeting peptides elicit therapeutic effects by inhibiting microRNA-21 in the glioblastoma animal models.
Not available
S-EPMC10658310 | biostudies-literature
TranscriptomicsExpression profiling of microRNA and mRNA on hepatic inflammation in high-fat induced murine model
The goal of this study was to identify and characterize of miRNA in the regulation of inflammatory responses of high-fat induced inflammation mouse model. In this study, we established a mouse model of high-fat-diet-induced inflammation to gain understanding on the biological functions deregulated ...
ORGANISM(S): Mus musculus 
2015-06-22 | E-GEOD-59042 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression perturbed by reptin shRNA in MCF7 subjected to normoxic and hypoxic conditions
In order to investigate the role of reptin methylation on the expression of hypoxia-responsive genes across the whole genome, we performed a microarray analysis from RNAs isolated from MCF7 cells expressing either control shRNA (shRNA) or reptin shRNA (shreptin) in normoxic and hypoxic conditions. M...
ORGANISM(S): Homo sapiens 
2010-07-13 | E-GEOD-15530 | biostudies-arrayexpress
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