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ProteomicsProteomic and single-cell transcriptomic dissection of human plasmacytoid dendritic cell response to influenza virus
Plasmacytoid dendritic cells [pDCs] represent a rare innate immune subset uniquely endowed with the capacity to produce substantial amounts of type-I interferons [IFN-I]. This function of pDCs is critical for effective antiviral defenses and has been implicated in autoimmunity. While IFN-I and selec...
ORGANISM(S): Human Plasmacytoid Dendritic Cell 
2021-11-12 | MSV000088375 | MassIVE
ProteomicsMouse ciliopathy-associated CPLANE proteins
Combining proteomics, in vivo imaging and genetic analysis of proteins linked to planar cell polarity (Inturned, Fuzzy and Wdpcp), we identified and characterized a new genetic module, which we term CPLANE (ciliogenesis and planar polarity effector), and an extensive associated protein network. CPLA...
ORGANISM(S): Mus musculus (Mouse) 
2016-08-15 | PXD004741 | Pride
"planar cell polarity” Mouse Ciliopathy “human genetics" Cplane 
UnknownA2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses.
Not available
S-EPMC10620403 | biostudies-literature
UnknownInhibition of lysine acetyltransferase KAT6 in ER<sup>+</sup>HER2<sup>-</sup> metastatic breast cancer: a phase 1 trial.
Not available
S-EPMC11333285 | biostudies-literature
UnknownRewiring endogenous genes in CAR T cells for tumour-restricted payload delivery.
Not available
S-EPMC12328239 | biostudies-literature
UnknownFOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy.
Not available
S-EPMC11062918 | biostudies-literature
ProteomicsROS transfer at peroxisome-mitochondria contact sites maintains mitochondrial redox homeostasis
Data deposited contain results from proximity-dependent biotinylation LC-MS (BioID) experiments in which T-REx Flp-In HEK293 cells express ACBD5 or PTPIP51 proteins fused to biotin carboxylase BirA.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-01 | MSV000093219 | MassIVE
UnknownRebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition.
Not available
S-EPMC10520344 | biostudies-literature
TranscriptomicsTranscriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport.
Cilia are ubiquitous cell surface projections that modulate various sensory- and motility based processes and are implicated in a growing number of multi-organ genetic disorders termed ciliopathies. As new components required for cilium biogenesis and function remain unidentified, we sought to furth...
ORGANISM(S): Caenorhabditis elegans 
2011-07-25 | E-GEOD-25633 | biostudies-arrayexpress
UnknownWhite Matter Abnormalities and Cognition in Aging and Alzheimer Disease.
Not available
S-EPMC12150229 | biostudies-literature
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