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TranscriptomicsMonopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.
The segregation of maternal centromeres away from the paternal ones during the first division of meiosis depends on the attachment of sister kinetochores to microtubules emanating from the same spindle pole. In budding yeast monopolar attachment requires the recruitment to kinetochores of a protein ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-4792 | biostudies-arrayexpress
GenomicsTargeted assembly of ectopic kinetochores to induce chromosome-specific segmental aneuploidies
Targeted assembly of ectopic kinetochores to induce chromosome-specific segmental aneuploidies
PRJEB59859 | ENA
ProteomicsArchitecture and Function of Holocentric CENP-A-Independent Inner Kinetochores
Kinetochores are essential macromolecular complexes anchoring chromosomes to the mitotic spindle, ensuring faithful cell division. Despite their critical role, the structural organization of kinetochores over large centromeric regions and across diverse species remains poorly understood. We present ...
ORGANISM(S): Spodoptera frugiperda 
2026-04-20 | PXD063391 | Pride
Kinetochore Insects Structure 
GenomicsRio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores
Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores
PRJNA904388 | ENA
TranscriptomicsSpo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion
BACKGROUND: Cells undergoing meiosis perform two consecutive divisions after a single round of DNA replication. During the first meiotic division, homologous chromosomes segregate to opposite poles. This is achieved by (1) the pairing of maternal and paternal chromosomes via recombination producing ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-4813 | biostudies-arrayexpress
OtherKinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment
Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly for microtubule attachment, but they also support robust sister chromatid cohesion at pericentromeres and facilitate replication of centromeric DNA early in S phase. Howe...
ORGANISM(S): Saccharomyces cerevisiae 
2013-06-06 | GSE41982 | GEO
TranscriptomicsPcs1 and Mde4 are inner centromere proteins required to prevent merotelic kinetochore orientation
Chromosome segregation depends on proper attachment of sister kinetochores to microtubules. Merotelic kinetochore orientation is an error which occurs when a single kinetochore is attached to microtubules emanating form opposite poles. Mechanisms preventing or correcting the merotelic attachment mus...
ORGANISM(S): Schizosaccharomyces pombe 
2010-06-10 | E-GEOD-5257 | biostudies-arrayexpress
TranscriptomicsKinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment
Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly for microtubule attachment, but they also support robust sister chromatid cohesion at pericentromeres and facilitate replication of centromeric DNA early in S phase. Howe...
ORGANISM(S): Saccharomyces cerevisiae 
2013-06-06 | E-GEOD-41982 | biostudies-arrayexpress
UnknownStructural basis of Stu2 recruitment to yeast kinetochores.
Not available
S-EPMC7909949 | biostudies-literature
UnknownSpindle assembly checkpoint activation and silencing at kinetochores.
Not available
S-EPMC8406419 | biostudies-literature
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