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ProteomicsKinase Inhibitor Pulldown Assay (KiP) for Clinical Proteomics (SureQuant)
Protein kinases are frequently dysregulated and/or mutated in cancer and represent essential targets for therapy. Accurate quantification is essential, but current approaches are inadequate. For breast cancer treatment for example, the identification and quantification of the protein kinase ERBB2 is...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046169 | Pride
Breast cancer Is-prm Surequant Kip 
ProteomicsKinase Inhibitor Pulldown Assay (KiP) for Clinical Proteomics
Protein kinases are frequently dysregulated and/or mutated in cancer and represent essential targets for therapy. Accurate quantification is essential, but current approaches are inadequate. For breast cancer treatment for example, the identification and quantification of the protein kinase ERBB2 is...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD044655 | Pride
Human Breast Cancer Kinase 
UnknownEvolutionary Approach of Intrinsically Disordered CIP/KIP Proteins.
Not available
S-EPMC6367352 | biostudies-literature
UnknownKinase inhibitor pulldown assay (KiP) for clinical proteomics.
Not available
S-EPMC10790396 | biostudies-literature
UnknownMultiple degradation pathways regulate versatile CIP/KIP CDK inhibitors.
Not available
S-EPMC3298816 | biostudies-literature
UnknownThe activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases.
Not available
S-EPMC4297576 | biostudies-literature
GenomicsIdentification of direct targets of Arabidopsis JAGGED in floral buds
JAGGED (JAG) is a regulatory gene that controls shoot organ growth in Arabidopsis. To reveal the molecular links between JAG and the cellular activities required for tissue growth, we used chromatin immunoprecipitation-high-throughput sequencing (ChIP-Seq). To reveal the genome-wide JAG binding site...
ORGANISM(S): Arabidopsis thaliana 
2014-03-05 | E-GEOD-51537 | biostudies-arrayexpress
UnknownA cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord.
Not available
S-EPMC1821088 | biostudies-literature
UnknownAn essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress.
Not available
S-EPMC5072439 | biostudies-literature
UnknownCortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells.
Not available
S-EPMC2953065 | biostudies-literature
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