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ProteomicsImmunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I (SureQuant data)
CD8+ T cells contribute to protective immunity to Mycobacterium tuberculosis (Mtb), but the principles that govern presentation of Mtb peptides on MHC class I (MHC-I) on the surface of infected macrophages for CD8+ T cell recognition are incompletely understood. Here, we use internal standard parall...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Homo sapiens (Human) 
2023-04-24 | PXD037843 | Pride
Macrophage Tuberculosis Mhc Immunopeptidomics Phagocyte Antigen presentation Tb 
ProteomicsA multi-omics analysis identifies retinol metabolism in fibroblasts as a key pathway in wound healing
In this analysis, we assessed the subtle changes in retinol metabolism during wound healing, by analyzing the proteome of normal and wounded skin in Vitamin A deficient -treated mice using targeted proteomics,analysis, SureQuant.
ORGANISM(S): Mus musculus (Mouse) 
2025-10-03 | PXD061256 | Pride
Skin Targeted proteomics Surequant Wound 
UnknownOptimizing SureQuant for Targeted Peptide Quantification: a Technical Comparison with PRM and SWATH-MS Methods.
Not available
S-EPMC11561883 | biostudies-literature
UnknownValidation and quantification of peptide antigens presented on MHCs using SureQuant.
Not available
S-EPMC12012165 | biostudies-literature
UnknownHigh-Throughput and High-Sensitivity Biomarker Monitoring in Body Fluid by Fast LC SureQuant IS-Targeted Quantitation.
Not available
S-EPMC11609441 | biostudies-literature
ProteomicsTargeteted quantification of RORDEPs in fasting plasma of healthy adult men
In this study, we investigated two bacterially derived polypeptides, RORDEP1 and RORDEP2, previously identified in human plasma through data-independent acquisition (DIA) mass spectrometry. To accurately measure the concentrations of these peptides in fasting plasma samples obtained from 59 healthy ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-04 | PXD057146 | Pride
Human Rumtor_00181-derived peptides (rordeps) Fasting plasma Targeted proteomics Lc-ms/ms 
ProteomicsHybrid-DIA: Intelligent Data Acquisition for Simultaneous Targeted and Discovery Phosphoproteomics in Single Spheroids
Achieving sufficient coverage of regulatory phosphorylation sites by mass spectrometry (MS)-based phosphoproteomics for signaling pathway reconstitution is challenging when analyzing tiny sample amounts. We present a novel hybrid data-independent acquisition (DIA) strategy (hybrid-DIA) that combines...
ORGANISM(S): Homo sapiens (Human) 
2023-05-18 | PXD038947 | Pride
Phosphoproteomics Targeted Discovery Proteomics Spheroids 
ProteomicsOptimizing SureQuant for Targeted Peptide Quantification: A Technical Comparison with PRM and SWATH-MS Methods
Bacterial infections are a major threat to human health worldwide. A better understanding of the properties and physiology of bacterial pathogens in human tissues is needed to develop urgently needed novel control strategies. Mass spectrometry-based proteomics could yield such data but identifying a...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) Homo Sapiens (ncbitaxon:9606) 
2024-07-02 | MSV000095213 | MassIVE
ProteomicsImpaired mitochondrial DNA maintenance in NAFLD: associations between mtDNA copy number, mtDNA damage and BER factors
Non-alcoholic fatty liver disease (NAFLD) is characterized by mitochondrial dysfunction and oxidative stress, potentially compromising mitochondrial DNA (mtDNA) integrity. The contribution of base excision repair (BER) to mtDNA maintenance in NAFLD remains poorly understood. Here, we analyzed mtDNA ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-17 | PXD075974 | Pride
Prm Leukocytes Mitochondria Evosep one Orbitrap astral Surequant 
ProteomicsHuman Plasma Discovery Proteomics
This study addresses this gap by conducting a direct comparison of eight platforms, representing both affinity-based and diverse mass spectrometry approaches, and covering over 13,000 proteins. By applying these platforms to the same cohort, we systematically assess their performance, identifying ke...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD067061 | Pride
Human Mass spec Proteomics Targeted mass spec Plasma Affinity 
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