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ProteomicsLong-read Proteogenomics Internal Standard triggered PRM (LRP-IS-PRM)
Long-read proteogenomic data was used to create sample-matched protein database for WTC11 sample. This includes many potential alternative protein isoforms (major and minor isoforms) per gene. The IS-PRM method called Tomahto was tested versus DDA to demonstrate improved coverage of isoform-specific...
ORGANISM(S): Homo sapiens (Human) 
2024-07-17 | PXD050909 | Pride
Proteogenomics Is-prm Tomahto 
ProteomicsLong-read Proteogenomics Internal Standard triggered PRM (LRP-IS-PRM)
Long-read proteogenomic data was used to create sample-matched protein database for WTC11 sample. This includes many potential alternative protein isoforms (major and minor isoforms) per gene. The IS-PRM method called Tomahto was tested versus DDA to demonstrate improved coverage of isoform-specific...
ORGANISM(S): Homo sapiens (Human) 
2024-07-17 | PXD050904 | Pride
Proteogenomics Is-prm Tomahto 
Genomics
IS-PRM for proteogenomic isoform discovery
PRJNA1090880 | ENA
UnknownLangat virus M protein is structurally homologous to prM.
Not available
S-EPMC114893 | biostudies-literature
UnknownLarge-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM).
Not available
S-EPMC4458725 | biostudies-literature
UnknownA single N-linked glycosylation site in the Japanese encephalitis virus prM protein is critical for cell type-specific prM protein biogenesis, virus particle release, and pathogenicity in mice.
Not available
S-EPMC2519568 | biostudies-literature
ProteomicsLarge-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring
Development, implementation, and evaluation of a new data acquisition scheme called internal standard triggered-parallel reaction monitoring (IS-PRM) to increase the scale of targeted quantitative experiments while retaining high detection and quantification performance. All the details about the da...
ORGANISM(S): Homo sapiens (Human) 
2016-02-09 | PXD001731 | Pride
Remote control Targeted proteomics Real-time data analysis Parallel reaction monitoring Quadrupole-orbitrap High resolution and accurate mass 
MetabolomicsLiquid Chromatography-Mass Spectrometry Quantification of Phytochemicals in Withania somnifera Using Data-Dependent Acquisition, Multiple-Reaction-Monitoring, and Parallel-Reaction-Monitoring with an Inclusion List

Characterization of botanical extracts by mass spectrometry-based metabolomics analysis helps in determining the phytochemical composition that underlies their bioactivity and potential health benefits, while also supporting reproducibility of effects in clinical trials. The quantification of sev...

2024-07-10 | MTBLS10418 | MetaboLights
UnknownIS-PRM-based peptide targeting informed by long-read sequencing for alternative proteome detection.
Not available
S-EPMC11014528 | biostudies-literature
UnknownNS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent.
Not available
S-EPMC3437442 | biostudies-literature
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