Sort   by:  
 Page size 
ProteomicsQuantitative modelling of B cell signaling in aggressive B cell lymphoma
The B cell receptor (BCR) signaling, required for the survival and maturation of B cells, is a major deregulated pathway in B cell lymphomas. Several mutations are known to enhance the tonic BCR signal in Burkitt lymphomas (BL) or to mimic an activated receptor in some diffuse large B cell lymphomas...
ORGANISM(S): Homo sapiens (Human) 
2024-09-14 | PXD047709 | Pride
Lymphoma Human Oncogenic signaling Stasnet 
ProteomicsFrequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma (Phospho-Proteome)
Recent exome-wide studies discovered frequent somatic mutations in the epigenetic modifier ZNF217 in primary mediastinal B cell lymphoma (PMBCL) and related disorders. As functional consequences of ZNF217 alterations remain unknown, we comprehensively evaluated their impact in PMBCL. Targeted sequen...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040928 | Pride
Znf217 Phosphoproteome Pmbcl Non-hodgkin lymphoma Genetics Mutation 
ProteomicsFrequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma (Global Proteome and PPI)
Recent exome-wide studies discovered frequent somatic mutations in the epigenetic modifier ZNF217 in primary mediastinal B cell lymphoma (PMBCL) and related disorders. As functional consequences of ZNF217 alterations remain unknown, we comprehensively evaluated their impact in PMBCL. Targeted sequen...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD034337 | Pride
Znf217 Pmbcl Non-hodgkin lymphoma Genetics Precision medicine Mutation Copy-number aberration 
UnknownQuantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network.
Not available
S-EPMC11469524 | biostudies-literature
UnknownTuning Solvent Miscibility: A Fundamental Assessment on the Example of Induced Methanol/ n-Dodecane Phase Separation.
Not available
S-EPMC6590496 | biostudies-literature
UnknownClinical characteristics of vulnerable populations hospitalized and diagnosed with COVID-19 in Buenos Aires, Argentina.
Not available
S-EPMC8102488 | biostudies-literature
UnknownThe structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus.
Not available
S-EPMC11731258 | biostudies-literature
UnknownA gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma.
Not available
S-EPMC7808386 | biostudies-literature
UnknownDe novo subtype and strain identification of botulinum neurotoxin type B through toxin proteomics.
Not available
S-EPMC3309144 | biostudies-literature
UnknownFrequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Not available
S-EPMC10624633 | biostudies-literature
Sort   by:  
 Page size