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ProteomicsIn-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Molecular communication between cancer cells and its stromal microenvironment is a key factor for cancer progression. Alongside classic secretory pathways, it has recently been proposed that small membranous vesicles are alternative mediators of intercellular communication. Exosomes carry an effecto...
ORGANISM(S): Homo sapiens (Human) 
2014-01-22 | PXD000695 | Pride
Ovarian cancer Exosome Proteomics 
ProteomicsIdentification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer.
Current protocols for the screening of prostate cancer cannot accurately discriminate clinically indolent tumors from more aggressive ones. One reliable indicator of outcome has been the determination of organ-confined versus nonorgan-confined disease but even this determination is often only made f...
ORGANISM(S): Homo sapiens (Human) 
2014-01-30 | PXD000400 | Pride
Proteomics Prostate cancer Human Expressed prostatic secretions 
ProteomicsComparative analysis of the human and mouse placental transcriptome and proteome
An important question for the use of the mouse as a model for studying human disease is the degree of functional conservation of genetic control pathways from human to mouse. The human and mouse placenta show structural similarities but there have been no systematic attempt to assess their molecular...
ORGANISM(S): Mus musculus 
2009-06-29 | E-GEOD-13299 | biostudies-arrayexpress
ProteomicsIn-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Molecular communication between cancer cells and its stromal microenvironment is a key factor for cancer progression. Alongside classic secretory pathways, it has recently been proposed that small membranous vesicles are alternative mediators of intercellular communication. Exosomes carry an effecto...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-23 | MSV000080278 | MassIVE
ProteomicsOrganelle resolved proteomics reveals new chordoma cell surface markers required for proliferation and association with outcome
Here, we used a proteomics approach to identify novel chordoma-specific cell-surface protein markers. Four established chordoma cell lines (U-CH17P, U-CH17M, U-CH17S and U-CH11R) were analyzed by quantitative proteomics using a comprehensive organellar fractionation approach based on differential ul...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-31 | MSV000089171 | MassIVE
ProteomicsTargeting axonal guidance dependencies in glioblastoma with ROBO1 CAR-T cells
Whole cell proteomics analysis of patient-matched glioblastoma models collected pre-treatment primary tumor (BT594) and post standard-of-care at first tumor recurrence (BT972).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-27 | MSV000094876 | MassIVE
ProteomicsPhosphoproteomic analysis of dopamine D2 receptor signaling reveals interplay of G protein- and beta-arrestin-mediated effects
Shotgun phosphoproteomics dataset investigating the influence of four balanced (quinpirole, sulpiride) and functionally selective (BM138, MS308) dopamine D2 receptor (D2R) ligands on protein phosphorylation in HEK293T cells transfected with the short isoform of D2R.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-11 | MSV000089457 | MassIVE
Proteomics,MultiomicsPSE115_PSM1063_mouse
Placentas from naturally-mated crosses of C57Bl/6J mice on embryonic day 17.5 were cut into thick slices. A scalpel blade was used to isolate the blood-red labyrin th tissue from the more poorly vascularized, and hence paler, spongiotrophoblast tissue, and to remove the superficial chorionic vascula...
ORGANISM(S): Mus Musculus 
2009-12-31 | PAe001560 | PeptideAtlas
ProteomicsSuper-SILAC analysis of human lung primary tumor-derived xenografts LC-MS/MS
Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancers, and is subdived into 2 major histological subtypes: adenocacinoma (ADC) and squamous cell carcinoma (SCC). Super-SILAC methodology was used to facilitate the quantitative comparisons of human primary tumor-derived xenograft proteom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-02 | MSV000079881 | MassIVE
TranscriptomicsGene expression analysis of head and neck squamous cell carcinoma cell lines and a control normal oral epithelial cell line
Microarrays were used to examine gene expression differences between human head and neck squamous cell carcinoma cell lines (FaDu, UTSCC8, UTSCC42a) grown in culture in comparison to a normal oral epithelial cell line. Gene expression data was integrated with global protein expression of head and ne...
ORGANISM(S): Homo sapiens 
2012-08-28 | E-GEOD-40185 | biostudies-arrayexpress
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