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TranscriptomicsRNA-Seq transcriptome profiling of in vitro cultures of migrating porcine primordial germ cells and porcine fetal fibroblasts of mini pig embryos between days 17-24 of gestation
Porcine embryonic germ cells (EGC) are cultured pluripotent cells derived from primordial germ cells (PGC). This study explored the possibilities to establish porcine EGC lines in the domestic breed pig more efficiently and from earlier embryonic stages than reported to date. In vitro culture of PGC...
ORGANISM(S): Sus scrofa 
2011-03-24 | E-GEOD-24220 | biostudies-arrayexpress
GenomicsInhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia [ChIP-Seq]
All-trans-retinoic acid (ATRA) has been successfully used in therapy of acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML) but the response of non-APL AML cases to ATRA-based treatment has been poor. Here we show that, via epigenetic reprogramming,...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-34725 | biostudies-arrayexpress
TranscriptomicsThe two-component system ChrSA is crucial for heme tolerance and interferes with HrrSA in heme-dependent gene regulation in Corynebacterium glutamicum
We recently showed that the two-component system (TCS) HrrSA plays a central role in the control of heme homeostasis in the Gram-positive soil bacterium Corynebacterium glutamicum. Here, we characterized the function of another TCS of this organism, ChrSA, which exhibits significant sequence similar...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2012-10-31 | E-GEOD-37327 | biostudies-arrayexpress
TranscriptomicsInhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia [Illumina HumanHT-12 gene expression array]
All-trans-retinoic acid (ATRA) has been successfully used in therapy of acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML) but the response of non-APL AML cases to ATRA-based treatment has been poor. Here we show that, via epigenetic reprogramming,...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-34672 | biostudies-arrayexpress
UnknownChanges in arterial oxygenation and self-reported oxygen use after lung volume reduction surgery.
Not available
S-EPMC2542439 | biostudies-literature
UnknownPulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema.
Not available
S-EPMC2817812 | biostudies-literature
UnknownSex differences in severe pulmonary emphysema.
Not available
S-EPMC1994221 | biostudies-literature
UnknownEffect of lung volume reduction surgery on resting pulmonary hemodynamics in severe emphysema.
Not available
S-EPMC1994220 | biostudies-literature
UnknownIntegrating health status and survival data: the palliative effect of lung volume reduction surgery.
Not available
S-EPMC2724716 | biostudies-literature
UnknownLung deflation and oxygen pulse in COPD: results from the NETT randomized trial.
Not available
S-EPMC3233645 | biostudies-literature
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