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ProteomicsA SUMO-Dependent Protein Network Regulates Chromosome Congression During Oocyte Meiosis
During Caenorhabditis elegans oocyte meiosis, a multi-protein complex localised between homologous chromosomes, the ring complex (RC), promotes chromosome congression through the action of the chromokinesin KLP-19. While some RC components are known, the mechanism of RC assembly has remained obscure...
ORGANISM(S): Caenorhabditis elegans 
2020-10-15 | PXD005202 | Pride
Klp-19 Pias C. elegans Sumoylation sites 
UnknownLoss of KLP-19 polar ejection force causes misorientation and missegregation of holocentric chromosomes.
Not available
S-EPMC1534123 | biostudies-literature
UnknownLack of chromokinesin Klp-19 creates a more rigid midzone and affects force transmission during anaphase in C. elegans.
Not available
S-EPMC10634869 | biostudies-literature
UnknownA SUMO-Dependent Protein Network Regulates Chromosome Congression during Oocyte Meiosis.
Not available
S-EPMC5222697 | biostudies-literature
UnknownRedundant microtubule crosslinkers prevent meiotic spindle bending to ensure diploid offspring in C. elegans.
Not available
S-EPMC10775986 | biostudies-literature
UnknownLateral microtubule bundles promote chromosome alignment during acentrosomal oocyte meiosis.
Not available
S-EPMC2760407 | biostudies-literature
TranscriptomicsGenomics of medulloblastoma identifies four distinct molecular variants
Recent genomic approaches have suggested the existence of multiple distinct subtypes of medulloblastoma. We studied a large cohort of medulloblastomas to determine how many subgroups of the disease exist, how they differ, and the extent of overlap between subgroups. We determined gene expression p...
ORGANISM(S): Homo sapiens 
2010-09-13 | E-GEOD-21140 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in rat mesenteric lymph nodes upon supplementation with conjugated linoleic acid during gestation and suckling
A summary of the work associated to these microarrays is the following: Diet plays a role in the development of the immune system, and polyunsaturated fatty acids can modulate the expression of a variety of genes. Human milk contains conjugated linoleic acid (CLA), a fatty acid that seems to contri...
ORGANISM(S): Rattus norvegicus 
2011-07-21 | E-GEOD-23004 | biostudies-arrayexpress
GenomicsDistribution of TAS2R38 bitter taste receptor phenotype and haplotypes among COVID-19 patients
The project aims at assessing the frequency of PAV and AVI alleles of TAS2R38 gene in COVID-19 patients (presenting both severe or non-severe symptoms) and comparing them to healthy subjects to corroborate, or not, the hypothesis that the PAV allele may act as a protecting factor towards SARS-CoV-2 ...
ORGANISM(S): Homo Sapiens 
2022-03-17 | PRJEB51612 | EVA
TranscriptomicsMNase-seq in Arabidopsis thaliana Col and h2a.w mutants
Col and h2a.w mutants (h2a.w6, h2a.w7, h2a.w6/7, h2a.w-2) bud sample were harvested. Nuclei extracted using Honda buffer was fragmented with mirococcal nuclease (MNase, NEB M0247S). The fragmented DNA was purified by phenol/chloroform/isoamyl alcohol (24:24:1) extraction, followed by ethanol precipi...
ORGANISM(S): Arabidopsis thaliana 
2025-04-23 | E-MTAB-14134 | biostudies-arrayexpress
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