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FTY720/Fingolimod, an FDA-approved drug for treatment of multiple sclerosis, has beneficial effects in the CNS that are not yet well understood, independent of its effects on immune cell trafficking. Here we show that FTY720 enters the nucleus where it is phosphorylated by sphingosine kinase 2 (SphK...
ORGANISM(S): Mus musculus 
Data from ProteomeXchange, PXD ID: PXD001432. File: SUK5557A8MA2__008-Spender2_3hP SUK5557A8MA2-40-215297.mzml. Published as part of . From the Abstract: {{i}} ... Periodate oxidation and aniline-catalyzed oxime ligation (PAL) technology was applied with subsequent quantitative LC-MS/MS (PAL-qLC-MS...
ORGANISM(S): Homo_sapiens_viruses, Human 
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