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ProteomicsRumen microbiome and effect of monensin
The time-resolved impact of monensin on the active rumen microbiome in a rumen-simulating technique (Rusitec) was studied with metaproteomic and metabolomic approaches. Upon monensin treatment, decreased catabolism linked to fiber degradation was observed by the reduced abundance of proteins assigne...
ORGANISM(S): Bos taurus (Bovine) 
2022-12-11 | PXD034099 | Pride
Prevotella Microbiome Monensin Rumen 
ProteomicsComplexome profiling of testis tissue in WT and ClpP-/- mice
Mutations in the gene for the mitochondrial matrix protease CLPP can cause human Perrault syndrome, which is characterized by male and female infertility, progressive sensorineural deafness, ataxia and leukoencephalopathy. This gene encodes a peptidase that is conserved since bacteria and localizes ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-17 | PXD035352 | Pride
Protease function Complexome profiling 
ProteomicsComplexome profiling of brain mitochondria from WT and ClpP-/- mice
Mutations in the gene for the mitochondrial matrix protease CLPP can cause human Perrault syndrome, which is characterized by male and female infertility, progressive sensorineural deafness, ataxia and leukoencephalopathy. This gene encodes a peptidase that is conserved since bacteria and localizes ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-17 | PXD036901 | Pride
Protease function Complexome profiling 
ProteomicsComplexome profiling of heart mitochondria from WT and ClpP-/- mice
Mutations in the gene for the mitochondrial matrix protease CLPP can cause human Perrault syndrome, which is characterized by male and female infertility, progressive sensorineural deafness, ataxia and leukoencephalopathy. This gene encodes a peptidase that is conserved since bacteria and localizes ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-17 | PXD036933 | Pride
Protease function Complexome profiling 
TranscriptomicsH. pylori infection blocks DNA damage induced apoptosis by T4SS-dependent upregulation of miR-155
The innate immune response against Helicobacter pylori is mainly controlled by pattern recognition receptors that lead to the up-regulation of pro-inflammatory cytokines. A new player in this field is the miR-155 being regulated by TLR ligands in monocytic derived cells influencing certain intracell...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-29388 | biostudies-arrayexpress
UnknownExploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2.
Not available
S-EPMC9827907 | biostudies-literature
UnknownMCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Not available
S-EPMC4880542 | biostudies-literature
ProteomicsTarget Landscape of Clinical Kinase Inhibitors
Here, we provide a comprehensive overview of the selectivity profiles of 242 kinase inhibitors currently in clinical trials. We screened available inhibitors against human protein kinases by using the Kinobead technology resulting in a drug matrix identifying the druggable kinome and related protein...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-12 | MSV000081932 | MassIVE
UnknownInternational guidelines for the imaging investigation of suspected child physical abuse (IGISPA): a protocol for a modified Delphi consensus study.
Not available
S-EPMC12506100 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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