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The aim of the present work was to investigate the effect of monensin on the in vitro growth of T. gondii tachyzoites and on the host cells (human brain microvascular endothelial cells - hBMECs). The hypotheses were that (1) inhibition of the WNT signalling pathway by monensin can reduce the growth ...
ORGANISM(S): Homo sapiens 
A549 cells were treated for 8 or 20 h using 20 ng/mL brefeldin A (BFA), 5 µM golgicide A (GCA), 10 µM monensin (MON) or the appropriate vehicle control (BFA/EtOH, MON/EtOH, GCA/DMSO).
ORGANISM(S): Homo sapiens 
Prevotella bryantii B14 was cultivated with monensin. Growth was monitored over a period of 9h with a broad range of monensin concentrations.
ORGANISM(S): Prevotella bryantii B14 
2021-10-13 | PXD026085 | Pride
Effect of monensin on apoptosis induction and oxidative stress in prostate cancer cells.
ORGANISM(S): Homo sapiens 
In order to better understand how the coccidiocide monensin affects T. gondii, we analyzed the effect of monensin on gene expression of intracellular parasites through microarrays. We compared RNA collected either from RH strain tachyzoites 24 hrs after invasion of human foreskin fibroblasts, or 24 ...
ORGANISM(S): Toxoplasma gondii 
The time-resolved impact of monensin on the active rumen microbiome in a rumen-simulating technique (Rusitec) was studied with metaproteomic and metabolomic approaches. Upon monensin treatment, decreased catabolism linked to fiber degradation was observed by the reduced abundance of proteins assigne...
ORGANISM(S): Bos taurus (Bovine) 
2022-12-11 | PXD034099 | Pride
This project aimed to identify key proteins dysregulated by monensin and itssynthetic analog, compound 12, in the triple-negative breast cancer (TNBC) cell line MDA-MB-231. Byanalyzing the molecular changes induced by these compounds, the study sought to elucidate themechanisms underlying their cyto...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD060697 | Pride
In order to better understand how the coccidiocide monensin affects T. gondii, we analyzed the effect of monensin on gene expression of intracellular parasites through microarrays.
ORGANISM(S): Toxoplasma gondii 
2010-11-06 | GSE25177 | GEO
Prevotella bryantii B14 was cultivated with monensin. Growth was monitored over a period of 72h including frequent sampling of cells.
ORGANISM(S): Prevotella bryantii B14 
2021-10-13 | PXD026057 | Pride
Expression profiling by high throughput sequencing of THP-1 cells treated with Monensin
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