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TranscriptomicsInterplay between c-Jun and TAp73M-NM-1/M-NM-2 contributes to the apoptosis-survival balance
The p53-family member p73 functions in various cellular signaling pathways and can have tumor suppressor properties. Several isoforms of p73 exist that differ considerably in their function. Whereas the functions of the N-terminal isoforms (TA and M-NM-^TNp73) and their opposing pro- and anti-apopto...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-15780 | biostudies-arrayexpress
GenomicsPhosphorylation of p53 Serine 46 contributes to target gene selectivity of p53 (ChIP-seq)
The tumor suppressor p53 plays a crucial role in cellular growth control inducing a plethora of cellular response pathways. The molecular mechanisms that discriminate between the distinct p53-responses towards different stress treatments have remained largely elusive. Here, we have analyzed the p53-...
ORGANISM(S): Homo sapiens 
2011-03-24 | E-GEOD-21939 | biostudies-arrayexpress
TranscriptomicsPhosphorylation of p53 Serine 46 contributes to target gene selectivity of p53 (Exon)
The tumor suppressor p53 plays a crucial role in cellular growth control inducing a plethora of cellular response pathways. The molecular mechanisms that discriminate between the distinct p53-responses towards different stress treatments have remained largely elusive. Here, we have analyzed the p53-...
ORGANISM(S): Homo sapiens 
2011-03-23 | E-GEOD-22184 | biostudies-arrayexpress
TranscriptomicsNcRNA profiling after Influenza A/WSN/33 infection I
A growing body of evidence suggests gene regulatory functions for the majority of non-protein-coding RNAs (ncRNAs). Besides small RNAs (sRNAs), the diverse class of long ncRNAs (lncRNAs) recently came into focus of research. So far, the relevance of lncRNAs in infection processes remains elusive. He...
ORGANISM(S): Homo sapiens 
2014-01-29 | E-GEOD-45397 | biostudies-arrayexpress
GenomicsHost genomic regions susceptible to damage during H. pylori infection
We identify here host genomic regions that are more likely to be damaged during an infection with the human gastirc pathogen Helicobacter pylori and characterize underlying features of them. By ChIP-seq we obtained global information about the localization of the DNA-damage marker H2AXpS139. We used...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-55699 | biostudies-arrayexpress
UnknownDNA methylation in human gastric epithelial cells defines regional identity without restricting lineage plasticity.
Not available
S-EPMC9801550 | biostudies-literature
UnknownEvidence for a crucial role of a host non-coding RNA in influenza A virus replication.
Not available
S-EPMC3929426 | biostudies-literature
TranscriptomicsNcRNA profiling after Influenza A/WSN/33 infection II
8h and 24h after A/WSN/33 infection (MOI 1) ncRNA profiling was performed A growing body of evidence suggests gene regulatory functions for the majority of non-protein-coding RNAs (ncRNAs). Besides small RNAs (sRNAs), the diverse class of long ncRNAs (lncRNAs) recently came into focus of research. S...
ORGANISM(S): Homo sapiens 
2014-01-29 | E-GEOD-45398 | biostudies-arrayexpress
TranscriptomicsEvidence for a Crucial Role of a Host Non-coding RNA in Influenza A Virus Replication
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-01-29 | E-GEOD-45399 | biostudies-arrayexpress
UnknownInflammation fuels colicin Ib-dependent competition of Salmonella serovar Typhimurium and E. coli in enterobacterial blooms.
Not available
S-EPMC3879352 | biostudies-literature
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