Sort   by:  
 Page size 
ProteomicsInteractome of C-terminally truncated CDK6
Pre/pro-B-cell lines were generated from bone marrow cells of Cdk6-/- mice by retroviral overexpression of the BCR-ABL (p185) fusion oncogene. These cell lines were transduced with constructs expressing HA-tagged versions of wildtype Cdk6 or of a C-terminally truncated variant of Cdk6 (HA-Cdk6-ΔC)....
ORGANISM(S): Mus musculus (Mouse) 
2024-12-19 | PXD058474 | Pride
Cyclin-dependent kinase 6 C-terminus Ip mass spec 
ProteomicsPhosphochromatome profiling of C-terminally truncated CDK6
Pre/pro-B-cell lines were generated from bone marrow cells of Cdk6-/- mice by retroviral overexpression of the BCR-ABL (p185) fusion oncogene. These cell lines were transduced with constructs expressing HA-tagged versions of wildtype Cdk6 or of a C-terminally truncated variant of Cdk6 (HA-Cdk6-ΔC)....
ORGANISM(S): Mus musculus (Mouse) 
2024-12-19 | PXD059037 | Pride
Cycline dependent kinase 6 C-lobe 
ProteomicsCDK6 degradation is counteracted by p16INK4A and p18INK4C in AML
Cyclin-dependent kinase 6 (CDK6) represents a novel therapeutic target for the treatment of certain subtypes of acute myeloid leukemia (AML). CDK4/6 kinase inhibitors have been widely studied in many cancer types and their effects may be limited by primary and secondary resistance mechanisms. CDK4/6...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD032216 | Pride
Cdk6 P16 Degrader P18 Cdkn2c Ink4 Cdkn2a Aml 
Sort   by:  
 Page size