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GenomicsRING1B binding in the 11 dpc embryonic tissues
We report the distribution of RING1B (one of Polycomb group factors) within the genome of mouse embryonic tissues. We prepared the chromatin from 11 dpc embryonic forebrain, midbrain, and forelimb buds and made chromatin precipitation with antibody against RING1B (mouse monoclonal antibody). High-th...
ORGANISM(S): Mus musculus 
2014-01-14 | E-GEOD-48464 | biostudies-arrayexpress
GenomicsEnhancer landscape of mouse developing midbrain at 11.5 dpc embryos
We report the distribution of histone H3K4me1 and H3K27ac within the genome of mouse embryonic midbrain. We prepared the chromatin from 11 dpc embryonic midbrain and made chromatin precipitation with antibody against H3K4me1 and H3K27ac (rabbit polyclonal antibody). High-throughput sequencing appli...
ORGANISM(S): Mus musculus 
2014-01-15 | E-GEOD-49652 | biostudies-arrayexpress
Transcriptomics4C-seq indicate interactive sites with the sequence close from Meis2 promoter
We report the distribution of interactive sites with the sequence close from Meis2 promoter within the genome of mouse embryonic forebrain. We prepared the chromatin from 11 dpc embryonic forebrain and made 3C (chromosomal conformation capture) library. High-throughput sequencing applied for the 3C ...
ORGANISM(S): Mus musculus 
2014-01-15 | E-GEOD-52281 | biostudies-arrayexpress
ProteomicsPCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment
Polycomb repressive complexes 1 and 2 (PRC1 and 2) repress lineage inappropriate genes during development to maintain proper cellular identities. To reveal the function of a variant PRC1 containing PCGF1 (PCGF1-PRC1), we prepared PCGF1 interacting proteins by immunoprecipitation and characterized th...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD036330 | Pride
Polycomb group proteins Mouse Pcgf1 Lc-ms/ms 
ProteomicsSKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced genes
Polycomb group (PcG) proteins are evolutionarily conserved repressors of developmental genes. Paradoxically, the same PcG proteins also play roles in gene activation via mechanisms that are not yet fully understood. Here, to reveal the function of S-phase kinase-associated protein 1A (SKP1A), an ess...
ORGANISM(S): Mus Musculus (mouse) 
2025-08-27 | PXD047552 | JPOST Repository
ProteomicsSKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced genes
Polycomb group (PcG) proteins are evolutionarily conserved repressors of developmental genes. Paradoxically, the same PcG proteins also play roles in gene activation via mechanisms that are not yet fully understood. Here, to reveal the function of S-phase kinase-associated protein 1A (SKP1A), an ess...
ORGANISM(S): Mus Musculus (mouse) 
2025-08-27 | PXD047556 | JPOST Repository
ProteomicsPCGF1-PRC1 safeguards recovery of nucleosome positioning during S-phase to ensure early hematopoiesis
Polycomb repressive complexes 1 and 2 (PRC1 and 2) repress lineage inappropriate genes during development to maintain proper cellular identities. To reveal the function of a variant PRC1 containing PCGF1 (PCGF1-PRC1), we prepared PCGF1 interacting proteins by immunoprecipitation and characterized th...
ORGANISM(S): Mus Musculus (mouse) 
2023-05-13 | PXD033883 | JPOST Repository
TranscriptomicsDDX20 knockdown effect on hepatocellular carcinoma cells
Analysis of DDX20 knockdown - hepatocellular carcinoma cells. The expression levels of genes driven by NF-kB and related with carcinogenesis, were significantly enhanced in DDX20-knockdown cells. One condition experiment, HepG2 vs. HepG2-DDX20 knockdown cells
ORGANISM(S): Homo sapiens 
2012-07-14 | E-GEOD-28088 | biostudies-arrayexpress
ProteomicsProteomic identification of PTMs of MAVS 1-200
To identify PTMs of MAVS, we overexpressed His-Flag-tagged hMAVS 1-200 in 293T cells and cell lysates were analyzed by LC-MS/MS.
ORGANISM(S): Homo Sapiens (human) 
2025-07-23 | PXD061814 | JPOST Repository
ProteomicsProteomic identification of PTMs of MAVS 1-200
To identify PTMs of MAVS, we overexpressed His-Flag-tagged hMAVS 1-200 in 293T cells and cell lysates were analyzed by LC-MS/MS.
ORGANISM(S): Homo Sapiens (human) 
2025-07-23 | PXD058405 | JPOST Repository
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