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GenomicsLong range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X
Dosage compensation in D. melanogaster males is achieved via targeting of the MSL complex to X chromosomal genes. This is proposed to involve initial sequence-specific recognition of the X at ~150-300 chromatin entry sites, and subsequent spreading to nearby active genes. Here we test a model in whi...
ORGANISM(S): Drosophila melanogaster 
2009-08-20 | E-GEOD-17729 | biostudies-arrayexpress
TranscriptomicsTranscriptional landscape of transkingdom communication between Candida albicans and Streptococcus gordonii
Recent studies have shown that the transcriptional landscape of the pleiomorphic fungus Candida albicans is highly dependent upon growth conditions. Here using a dual RNA-seq approach we identified 299 C. albicans and 72 Streptococcus gordonii genes that were either up- or down-regulated specificall...
ORGANISM(S): Candida albicans 
2015-06-22 | E-GEOD-68477 | biostudies-arrayexpress
UnknownSystemic above- and belowground cross talk: hormone-based responses triggered by Heterodera schachtii and shoot herbivores in Arabidopsis thaliana.
Not available
S-EPMC4765779 | biostudies-literature
TranscriptomicsLoss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation
Background: Precise spatiotemporal control of gene expression is essential for the establishment of correct cell numbers and identities during brain development. This process involves epigenetic control mechanisms, such as those mediated by the polycomb group protein Ezh2 that catalyzes trimethylat...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-74538 | biostudies-arrayexpress
TranscriptomicsThe Stockholm Atherosclerosis Gene Expression (STAGE) study: Global Gene Expression data from coronary and carotid artery disease patients
Tissue samples have been isolated during corornary artery by-pass grafting (CABG)surgery from the atheroscelrotic arterial wall (AAW, aortic root puncture for proxmal ligation of by-pass vessel), non-atherosclertoci arterial wall (NAAW, distal part of mammary artery used a graft for LAD), liver, sk...
ORGANISM(S): Homo sapiens 
2012-08-21 | E-GEOD-40231 | biostudies-arrayexpress
TranscriptomicsThe histone chaperone CAF-1 safeguards somatic cell identity during transcription factor-induced reprogramming
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-12-10 | E-GEOD-66534 | biostudies-arrayexpress
TranscriptomicsCAF-1 safeguards somatic cell identity during factor-induced reprogramming
Cellular differentiation involves profound changes in the chromatic landscape, yet the mechanisms by which somatic cell identity is subsequently maintained remain incompletely understood. To further elucidate regulatory pathways that safeguard the somatic state, we performed two comprehensive RNAi ...
ORGANISM(S): Mus musculus 
2015-12-10 | E-GEOD-72741 | biostudies-arrayexpress
TranscriptomicsAll-iPS cell mice generated from terminally differentiated B cells
The generation of induced pluripotent stem cells (iPSCs) often results in aberrant silencing of the imprinted Dlk1-Dio3 gene cluster, which compromises their ability to generate entirely iPSC-derived mice (“all-iPSC mice”). Here, we show that reprogramming in the presence of ascorbic acid attenu...
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-34761 | biostudies-arrayexpress
TranscriptomicsNucleosome occupancy changes in mammalian cell differentiation and reprogramming (microarray)
Embryonic stem cells (ESCs) and induced-pluripotent stem cells (iPSCs) self-renew and differentiate into an array of cell types in vitro and in vivo. A complex network of genetic and epigenetic pathways regulates the self-renewal and differentiation of these pluripotent cells, and the structure and ...
ORGANISM(S): Mus musculus 
2014-07-31 | E-GEOD-59061 | biostudies-arrayexpress
ProteomicsAnalysis of the MAGED2 interactome
The MAGED2 interactome was analyzed in HEK293T cells using three different strategies.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080703 | MassIVE
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