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TranscriptomicsAn intrahepatic gene expression signature of enhanced immune activity predicts response to peginterferon and adefovir in chronic hepatitis B patients
In this study we aimed to identify a baseline intrahepatic transcriptional signature associated with response in chronic hepatitis B patients treated with peginterferon-alfa-2a (peg-IFN) and adefovir. Liver gene expression values of patients with combined response (responders; n=9) and non-response ...
ORGANISM(S): Homo sapiens 
2014-12-19 | E-GEOD-54747 | biostudies-arrayexpress
UnknownA genetic variation in fucosyltransferase 8 accelerates HIV-1 disease progression indicating a role for N-glycan fucosylation.
Not available
S-EPMC10552802 | biostudies-literature
UnknownIdentification of 2-(4-N,N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo.
Not available
S-EPMC9241302 | biostudies-literature
ProteomicsAfucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through NK cell mediated killing
A series of monoclonal antibodies (mAbs) against human immune deficiency virus (HIV) were prepared utilizing different variable regions targeting HIV epitopes in combination with glycoengineering to produce mAbs with low Fc fucosylation. This dataset pertains to the Fc N-glycosylation analysis of th...
ORGANISM(S): Homo sapiens (Human) 
2024-07-30 | PXD053363 | Pride
Lc-ms Monoclonal antibodies Hek-293f cells Antibody glycosylation 
UnknownSimilar Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Similar Nucleocapsid Antibody Levels in People With Well-Controlled Human Immunodeficiency Virus (HIV) and a Comparable Cohort of People Without HIV.
Not available
S-EPMC8755357 | biostudies-literature
UnknownA Prospective Five-Year Follow-up After peg-Interferon Plus Nucleotide Analogue Treatment or no Treatment in HBeAg Negative Chronic Hepatitis B Patients.
Not available
S-EPMC9168707 | biostudies-literature
UnknownImmune phenotype and function of natural killer and T cells in chronic hepatitis C patients who received a single dose of anti-MicroRNA-122, RG-101.
Not available
S-EPMC5850982 | biostudies-literature
TranscriptomicsSimilarities and differences between macrophage polarized gene profiles (Illumina)
The human AA dataset 5 includes the gene expression profile of monocyte-derived macrophages isolated from blood donor buffy coats and plated on TCP in medium containing 10% autologous serum. Cells were stimulated for 120 hours with 50 ng/ml of IL-4, 50 U/ml of IFN-γ plus 12.5 ng/ml of TNF-α, 50 ng/m...
ORGANISM(S): Homo sapiens 
2013-07-26 | E-GEOD-49240 | biostudies-arrayexpress
UnknownBiomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms.
Not available
S-EPMC10244452 | biostudies-literature
UnknownImmune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing.
Not available
S-EPMC7610787 | biostudies-literature
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