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ProteomicsExome-based proteogenomics of HEK-293 human cell line: coding genomic variants identified at the level of shotgun proteome
Genomic and proteomic data were integrated into the proteogenomic workflow to identify coding genomic variants of Human Embryonic Kidney 293 (HEK-293) standard cell line at the proteome level. Shotgun proteome data published by Geiger et al (2012) and obtained in this work for HEK-293 were searched ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080712 | MassIVE
ProteomicsProteomic analysis of protein profile of blood serum of patients with autism children
A comparative panoramic mass spectrometric analysis of serum samples from three families with children with autistic disorders was carried out. The total number of examined samples was nine, including four control samples from healthy parents, and five samples from autistic children.
ORGANISM(S): Homo sapiens (Human) 
2016-11-01 | PXD005193 | Pride
Autism Esi-ms/ms 
ProteomicsTear proteome revealed association of S100A family proteins and mesothelin with thrombosis in elderly patients with retinal vein occlusion
Tear samples collected from patients with central retinal vein occlusion (n=58) and group of healthy volunteers (n=30) were analyzed using a proteomic label-free absolute quantitative ap-proach. We found a large proportion (458 proteins with a frequency > 0.6) of tear proteome shared between healthy...
ORGANISM(S): Homo sapiens (Human) 
2022-12-13 | PXD037021 | Pride
Retinal vein occlusion  retinal hemostasis  s100a protein  mesothelin  inflammation 
ProteomicsProteome profiling of myogenic differentiation of alveolar mucosa multipotent mesenchymal stromal cells revealed an unexpected deviation between 2D monolayer and 3D spheroid model cultures.
Recently, it has been proposed to employ three-dimensional cultivation of cell in spheroids that contributes more proper physiological conditions in matrix extracellular space architecture and cell morphology accompanied by appropriate intracellular biomechanical organization of cytoskeleton and ene...
ORGANISM(S): Homo sapiens (Human) 
2021-11-15 | PXD015410 | Pride
Myogenesis  monolayer culture  spheroid culture  cytoskeleton  mitochondria  autophagy 
UnknownConstitutive and activation-dependent phosphorylation of lymphocyte phosphatase-associated phosphoprotein (LPAP).
Not available
S-EPMC5565103 | biostudies-literature
TranscriptomicsTranscriptional profiling of CD133+/high vs CD133-/low cell populations of Caco2, HT-29 and HUH7 cell lines
Transcriptional profiling of CD133+/high vs CD133-/low cell populations of Caco2, HT-29 and HUH7 cell lines. Further in silico analysis of differentially expressed transcripts and proteins in CD133+/high vs CD133-/low cell populations revealed several potential key molecular regulators of CD133. In ...
ORGANISM(S): Homo sapiens 
2022-09-24 | E-MTAB-11779 | biostudies-arrayexpress
UnknownAssociation of Proteins Modulating Immune Response and Insulin Clearance During Gestation with Antenatal Complications in Patients with Gestational or Type 2 Diabetes Mellitus.
Not available
S-EPMC7226479 | biostudies-literature
UnknownMolecular Profiling of Athletes Performing High-Intensity Exercises in Extreme Environments.
Not available
S-EPMC9963857 | biostudies-literature
UnknownDUOX1 Gene Missense Mutation Confers Susceptibility on Type 2 Amiodarone-Induced Thyrotoxicosis.
Not available
S-EPMC9964217 | biostudies-literature
ProteomicsUpdate on virtual-experimental 2DE approach in chromosome-centric human proteome project
In the boundaries of chromosome-centric Human Proteome Project c-HPP to obtain information about proteoforms coded by chromosome 18, several cell lines were analyzed. In our study we have been using proteoform separation by 2DE (sectional analysis) and semi-virtual 2DE with following shotgun mass-sp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-12 | MSV000086448 | MassIVE
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