Sort   by:  
 Page size 
ProteomicsDICER-interacting partners in juvenile mouse testes
DICER has a well-characterized role in the processing of microRNAs (miRNAs) and small interfering RNAs (siRNA) that are important for post-transcriptional gene regulation. Emerging evidence suggests that DICER also has several non-canonical functions beyond miRNA/siRNA biogenesis, for example in tra...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-03 | PXD017772 | Pride
Mouse testis Germ cells Dicer 
ProteomicsThe late chromatoid body component TSSK2 associates with translational machinery in elongating spermatids in mice
Spermatogenesis culminates in a dramatic morphological transformation, including a tight compaction of the chromatin and nuclear re-shaping that largely silences transcription. Due to transcriptional silencing, the production of the sperm-specific proteins needed for the morphological transformation...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-27 | PXD065042 | Pride
Spermatogenesis Rnp granules Elongating spermatids Chromatoid body Tssk2 Male fertility Translation 
ProteomicsSmg6 interacting partners in mouse
Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA turnover pathway that depends on the endonuclease SMG6. Here, we show that SMG6 is essential for male germ cell differentiation in mice. Germ-cell conditional knockout (cKO) of Smg6 induces extensive transcriptome misregulatio...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-01 | PXD037090 | Pride
Smg7 Chromatoid body Mouse Smg6 
TranscriptomicsThe Atlas of Chromatoid Body Components [RNA-seq]
The genome of male germ cells is actively transcribed during spermatogenesis to produce phase-specific protein coding mRNAs and a considerable amount of different non-coding RNAs. Ribonucleoprotein (RNP) granule-mediated RNA regulation provides a powerful means to secure the quality and correct expr...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-54286 | biostudies-arrayexpress
TranscriptomicsThe Atlas of Chromatoid Body Components
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-54288 | biostudies-arrayexpress
Sort   by:  
 Page size