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TranscriptomicsExpression data from mouse kidney epithelial cells
Fumarate hydratase (FH) is the enzyme in the Krebs cycle, which transforms fumarate to malate. Loss of fumarate hyrdragase leads to hereditary leiomyomatosis and renal cell cancer (HLRCC). The biallelic inactivation has been highly accumulated in FH-deficient cells and is considered a major pro-onco...
ORGANISM(S): Mus musculus 
2014-11-19 | E-GEOD-63438 | biostudies-arrayexpress
UnknownSynthesis and crystal structure of di-aqua-bis-(hexa-methyl-enetramine-κN)bis-(thio-cyanato-κN)cobalt(II)-hexa-methyl-ene-tetra-mine-aceto-nitrile (1/2/2).
Not available
S-EPMC8587985 | biostudies-literature
TranscriptomicsExpression of virulent and non-virulent E.histolytica in contact with the human colon
Evaluation of transcript levels of two strains E.Histolytica (virulent and avirulent) in two conditions (in culture or in contact with a human colon explant)
ORGANISM(S): Entamoeba histolytica 
2012-08-01 | E-MTAB-1201 | biostudies-arrayexpress
UnknownSynthesis, crystal structure and thermal properties of poly[bis-[μ2-3-(amino-meth-yl)pyridine]-bis-(thio-cyanato)-cobalt(II)].
Not available
S-EPMC8025872 | biostudies-literature
UnknownSynthesis, crystal structure and thermal properties of poly[bis-[μ-3-(amino-meth-yl)pyridine-κ2 N:N']bis(thio-cyanato-κN)manganese(II)].
Not available
S-EPMC8340975 | biostudies-literature
TranscriptomicsGene expression profiling of skeletal myoblast differentiation and exposure to TNF-alpha or IGF1
Skeletal myocyte differentiation involves fusion of myoblasts to multinucleated myotubes. In vitro differentiation can be induced by serum withdrawal. The differentiation process is negatively regulated by pathological concentrations of TNF-alpha but can be positively regulated by IGF1. This study f...
ORGANISM(S): Mus musculus 
2015-04-05 | E-MTAB-3474 | biostudies-arrayexpress
UnknownBi-allelic variants in OGDHL cause a neurodevelopmental spectrum disease featuring epilepsy, hearing loss, visual impairment, and ataxia.
Not available
S-EPMC8715183 | biostudies-literature
TranscriptomicsSingle-cell Atlas of intrahepatic T cells reveals a population of liver-resident naive-like CD4+ T cells expanded in primary sclerosing cholangitis
The composition of intrahepatic immune cells in primary sclerosing cholangitis (PSC) and their contribution to disease pathogenesis is widely unknown. We here generated a single-cell atlas of intrahepatic T cells in PSC, a type of immune cells that has previously been involved in the pathogenesis of...
ORGANISM(S): Homo sapiens 
2021-03-27 | E-MTAB-10143 | biostudies-arrayexpress
ProteomicsLipid nanotubes unmask neutrophils for complement attack
Neutrophils, critical components of innate immunity, undergo significant morphological changes during phagocytosis. In this study, we demonstrate that neutrophils exposed to shear stress generate lipid nanotubes (NTs) with a unique composition. Compared to the proteome of whole neutrophils, NTs nota...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD064111 | Pride
Complement system Shear stress Extracellular vesicles Neutrophils Polytrauma Vasculitis 
TranscriptomicsGene expression analysis of SDH-deficient immortalized kidney epithelial cells
Succinate dehydrogenase (SDH) is a mitochondrial protein complex responsible for the oxidation of succinate to fumarate in the tricarboxylic acid cycle. Loss-of-function mutations in any of the SDH genes are associated with susceptibility to develop neu-roendrocrine neoplasms and renal cell carcinom...
ORGANISM(S): Mus musculus 
2016-01-22 | E-MTAB-4349 | biostudies-arrayexpress
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