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TranscriptomicsMiR-221 mediated gene expression in human PCa cells
MiR-221 overexpression leads to activation of apoptosis, growth arrest and reduced invasivness in PCa cells. Interaction of miR-221 with potential target genes was analyzed by a genome wide expression profiling.. Regulation of selected genes and proteins identified in the gene array analysis was con...
ORGANISM(S): Homo sapiens 
2014-03-27 | E-GEOD-45627 | biostudies-arrayexpress
ProteomicsIdentification of non-specific phosphatases in TCA cycle regulation
Protein phosphorylation is a well-established post-translational mechanism that regulates protein functions and metabolic pathways. It has been shown that several plant mitochondrial proteins are phosphorylated in a reversible manner. However, the identity of the phosphatases/kinases involved in thi...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2021-04-01 | PXD018412 | JPOST Repository
TranscriptomicsStem cell factor Sox2 regulates the tumorigenic potential in human gastric cancer cells
Gastric cancer is still one of the most common causes of cancer-related death worldwide, which is mainly attributable to late diagnosis and poor treatment options. Infection with H. pylori, different environmental factors and genetic alterations are known to influence the risk of developing gastric ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-42937 | biostudies-arrayexpress
MetabolomicsOperation of a TCA cycle subnetwork in the mammalian nucleus

Nucleic acid and histone modifications critically depend on tricarboxylic acid (TCA) cycle for substrates and co-factors. Although a few TCA cycle enzymes have been reported in the nucleus, the corresponding pathways are considered to operate in mitochondria. Here, we show that a part of the...

2022-06-15 | MTBLS2235 | MetaboLights
TranscriptomicsAnalysis of the CcpA regulon in Staphylococcus aureus
Background The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram positive bacteria. It functions as a catabolite repressor or activator, allowing the bacteria to utilize the preferred carbon sou...
ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman 
2010-06-24 | E-GEOD-12614 | biostudies-arrayexpress
UnknownEffectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel.
Not available
S-EPMC8482809 | biostudies-literature
UnknownPrognosis and quality of life in patients with locally advanced rectal cancer after abdominoperineal resection in the CAO/ARO/AIO-04 randomized phase 3 trial.
Not available
S-EPMC11825916 | biostudies-literature
UnknownStroke genetics informs drug discovery and risk prediction across ancestries.
Not available
S-EPMC9524349 | biostudies-literature
UnknownRivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Not available
S-EPMC6662613 | biostudies-literature
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