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ProteomicsProteomics based identification and validation of biomarkers for AMD
Age related macular degeneration (AMD) is one of the leading causes of irreversible central vision loss in the elderly population. According to the WHO estimates, AMD globally ranks third in causing vision impairment with a blindness prevalence of 8.7%.There is no cure for AMD; however,if it is diag...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD007531 | Pride
Amd Urine Biomarkers 
UnknownRNAi mediated Tiam1 gene knockdown inhibits invasion of retinoblastoma.
Not available
S-EPMC3737373 | biostudies-literature
TranscriptomicsGene expression profiling of retinoblastoma Y79 cell line treated with scopoletin from Morinda citrifolia in vitro
Retinoblastoma Y79 cell line was treated with scopoletin in vitro and RNA was isolated for microarray experiment to study the changes in the whole gene expression profiling in the Y79 cell line. The study identified 1675 up-regulated genes (>1.0 fold) and 1879 down-regulated genes (<-1 fold) in resp...
ORGANISM(S): Homo sapiens 
2010-08-18 | E-GEOD-16998 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of retinoblastoma Y79 cell line post EpCAM silencing using siRNA
Retinoblastoma Y79 cell line was treated with specific siRNA to silence EpCAM gene expression in vitro and RNA was isolated for microarray experiment to study the changes in the whole gene expression profiling in the Y79 cell line. The study identified 465 up-regulated genes (>1.0 fold) and 205 down...
ORGANISM(S): Homo sapiens 
2010-08-18 | E-GEOD-16991 | biostudies-arrayexpress
UnknownEpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer.
Not available
S-EPMC4503753 | biostudies-literature
UnknownTranscriptomic profiling to investigate the therapeutic potential and medicinal properties of Momordica cymbalaria.
Not available
S-EPMC12484536 | biostudies-literature
UnknownEpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex.
Not available
S-EPMC4307906 | biostudies-literature
UnknownNucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry-based imaging.
Not available
S-EPMC5023409 | biostudies-literature
TranscriptomicsDifferential expression of miRNAs in Retinoblastoma cells (Y79) in response to anti-HMGA2 siRNA treatment
The main objective of the study is to identify the de-regulated miRNAs in association with HMGA2 (oncogene) in the Retinoblastoma tumorus. The present experiment was carried out using Y79 (Retinoblastoma cell line), as the invitro model of Retinoblastoma tumor. The HMGA2 transcripts were silenced us...
ORGANISM(S): Homo sapiens 
2013-10-26 | E-GEOD-51696 | biostudies-arrayexpress
TranscriptomicsmiRNA expression studies in uveal melanoma (South Asian-Indian population).
To predict differentially expressed miRNAs between monosomy 3 and disomy 3, and to associate these miRNAs with the clinico-pathological parameters in South Asian Indian population with uveal melanoma (UM). The study consists of six uveal melanoma primary tumour tissues of South Asian-Indian populati...
ORGANISM(S): Homo sapiens 
2015-05-14 | E-GEOD-68828 | biostudies-arrayexpress
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