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ProteomicsData independent MS phenotyping of patient derived melanoma cell lines
Phenotyping of patient derived Stage III and IV melanoma cell lines to predict drug response
ORGANISM(S): Homo sapiens (Human) 
2018-10-11 | PXD002725 | Pride
Human Melanoma Swath Drug resistance 
ProteomicsData independent MS phenotyping of melanoma tissue specimens
Phenotyping of Stage III BRAF or NRAS mutant melanoma tissue specimens to predict drug response and patient survival
ORGANISM(S): Homo sapiens (Human) 
2018-10-11 | PXD007083 | Pride
Human Melanoma Swath Drug resistance 
OtherOnline peptide fractionation using a multiphasic microfluidic LC chip improves reproducibility and detection limits for quantitation in discovery and targeted proteomics.
Data from ProteomeXchange, PXD ID: PXD001464. Experiment: 1hRP, file: CL_1hRP_rep4-Cell_Lysate_rep4.mgf. Published as part of Mol Cell Proteomics. 2015 Apr 7 . From the Abstract: {{i}} Comprehensive proteomic profiling of biological specimens usually requires multi-dimensional chromatographic pepti...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210037376 | GPMDB
Resource Reanalysis 
ProteomicsMultiplexed complexome profiling using tandem mass tags
Complexome profiling is a rapidly spreading, powerful approach to gain insight into the nature of protein complexes. It identifies and quantifies protein complexes separated into multiple fractions of increasing molecular mass using mass spectrometry-based, label-free bottom-up proteomics. Complexom...
ORGANISM(S): Homo sapiens (Human) 
2021-08-20 | PXD023211 | Pride
Complexome profiling  multiplexed complexomics  tandem mass tags  protein complexes 
ProteomicsIdentification of Bona Fide Targets of AMPylating Fic-enzymes by Substrate Mediated Covalent Capture
Many pathogenic bacteria utilize posttranslational modifications to manipulate central components of the host cell functions. Often, the released enzymes belong to the large Fic-family, causing target modification with nucleotide monophosphates. Due to the lack of a generic method for the identifica...
ORGANISM(S): Homo sapiens (Human) 
2020-07-09 | PXD015599 | Pride
Fic enzymes Post-translational modifications Ampylation Host-pathogen interactions 
ProteomicsMultiphasic chip performance characterization using human thyroid cancer cell line SW1736 and human plasma
Development of an online peptide fractionation system comprising a multiphasic LC chip that integrates reversed phase and strong cation exchange chromatography upstream of the MS based on the multi-dimensional protein identification technology (mudPIT). Chips were assessed in terms of chromatographi...
ORGANISM(S): Homo sapiens (Human) 
2015-04-15 | PXD001464 | Pride
Chip lc-msms Thyroid cancer cell line Human plasma Multiphasic lc chip separation 
ProteomicsProteome analysis of human visceral and subcutaneous adipocytes identifies altered metabolic control points
Adipose tissue is a primary regulator of energy balance and metabolism. The distribution of adipose tissue depots is of clinical interest because the accumulation of upper-body subcutaneous (ASAT) and visceral adipose tissue (VAT) is associated with cardiometabolic diseases, whereas lower-body glute...
ORGANISM(S): Homo sapiens (Human) 
2021-04-19 | PXD018314 | Pride
Lipid metabolism Proteomics Swathßms Adipose tissue Obesity 
ProteomicsStructural basis of chaperone regulation by a post-translational modification
The Hsp70 chaperone BiP is covalently modified with adenosine monophosphate (referred to as AMPylation) in order to adapt its activity to the fluctuating folding load within the endoplasmic reticulum. This modification is catalyzed by the only human representative of the family of filamentation indu...
ORGANISM(S): Homo sapiens (Human) 
2021-04-27 | PXD022869 | Pride
Hype Ampylation Hsp70 chaperone bip 
ProteomicsThe role of HnrnpF/H as a driver of Oligoteratozoospermia
Male subfertility or infertility is a common condition often characterized by men producing a low number of sperm with poor quality. To gain insight into this condition, we performed a quantitative proteomic analysis of semen samples obtained from infertile and fertile men.
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD046594 | Pride
Human Sperm Male infertility Swath-ms 
ProteomicsProteomics of Plasma samples from COVID19 patients
Coagulopathy is a hallmark finding in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is associated with an increased risk of death from venous and arterial thromboembolic complications. SARS-CoV-2 infection can lead to microvascular thrombosis that contribute...
ORGANISM(S): Homo sapiens (Human) 
2021-08-20 | PXD020279 | Pride
Pulmonary thromboinflammation Covid19 Sars-cov-2 infection Pulmonary thrombosis Pulmonary thromboembolism 
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