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The Patancheru area near Hyderabad in India is recognized as a key link in the global supply chain for many bulk drugs. A central treatment plant receives wastewater from about 90 different manufacturers and the resulting complex effluent has contaminated surface, ground and drinking water in the re...
ORGANISM(S): Rattus norvegicus 
A 50-mer oligonucleotide microarray was designed for large-scale gene expression analysis in Z. viviparus. To measure the expression of the probes and the corresponding assembled transcripts, the pool of mRNA used for the sequencing was hybridized. 1 Sample hybridized to microarray used to evaluate ...
ORGANISM(S): Zoarces viviparus 
Background & Aims: In gastrointestinal stromal tumors (GIST) KIT exon 11 deletions are associated with poor prognosis. The aim of this study was to determine the gene expression profile of GIST carrying KIT exon 11 deletions and to identify genes associated with poor prognosis. Methods: Expression p...
ORGANISM(S): Homo sapiens 
Patancheru, near Hyderabad, India, is a major production site for the global bulk drug market. About 90 manufacturers send their wastewater to a common treatment plant in Patancheru. Extraordinary high levels of a wide range of pharmaceuticals have recently been demonstrated in the treated effluent....
ORGANISM(S): Oncorhynchus mykiss 
Background: Diclofenac is a non-steroidal anti-inflammatory drug frequently found in the aquatic environment. Previous studies have reported histological changes in the liver, kidney and gills of fish at concentrations similar to those measured in treated sewage effluents (~1 µg/L). Analyses or pred...
ORGANISM(S): Oncorhynchus mykiss 
Effluents from sewage treatment plants contain a mixture of micropollutants with the potential of harming aquatic organisms. Thus, addition of advanced treatment techniques to complement existing conventional methods has been proposed. Some of the advanced techniques could, however, potentially prod...
ORGANISM(S): Oncorhynchus mykiss 
Exome sequencing of nine PCC/PGL tumors, SF and FFPE samples
One out of ten patients with pheochromocytoma (PCC) and paraganglioma (PGL) develop malignant disease. Today there are no reliable pathological methods to predict malignancy at the time of diagnosis. Tumors harboring mutations in the succinate dehydrogenase subunit B (SDHB) gene often metastasize bu...
Investigation of transcriptome expression changes in liver tissue of rainbow trout exposed beclomethasone diproprionate (1 M-BM-5g/L nominal concentration) in a flow through set up for 2 weeks A four chip (x12) study using total RNA prepared from liver.
ORGANISM(S): Oncorhynchus mykiss 
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