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ProteomicsAncient tooth enamel proteomes to help understand post mortem protein degradation over millions of years
The tooth enamel proteome is enzymatically broken down during development, which leads to a heterogenous distribution of remaining peptides of a protein sequence in a grown individual's enamelome. After death of the organism, the heterogeneous distribution of remaining peptides may be enhanced, as t...
ORGANISM(S): Equidae Proboscidea <placentals> 
2025-05-06 | PXD048972 | Pride
Proboscidea Paleoproteomics Equidae Ancient Enamel 
GenomicsSingle-cell DNA methylome sequencing and bioinformatic inference of epigenetic cell state dynamics
Here we describe a method for whole genome bisulfite sequencing in very small cell populations (µWGBS) and in single cells (scWGBS). Our method is optimized for profiling DNA methylation in many samples at low coverage, and we developed a bioinformatic method that uses collections of single-cell met...
ORGANISM(S): Mus musculus 
2015-02-25 | E-GEOD-65196 | biostudies-arrayexpress
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