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GenomicAnalysis of AR Gene Rearrangements in Prostate Cancer

Molecularly-targeted therapies for advanced prostate cancer include castration modalities that suppress ligand-dependent transcriptional activity of the androgen receptor (AR). However, persistent AR signaling undermines therapeutic efficacy and promotes progression to lethal castration-resistant...

phs001223 | dbGaP
MetabolomicsReactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...
2019-05-22 | MTBLS593 | MetaboLights
UnknownACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer.
Not available
S-EPMC5512571 | biostudies-literature
UnknownGaliellalactone inhibits the STAT3/AR signaling axis and suppresses Enzalutamide-resistant Prostate Cancer.
Not available
S-EPMC6251893 | biostudies-literature
ProteomicsProfiling the proteome of Mycobacterium tuberculosis during dormancy and reactivation
Tuberculosis, caused by Mycobacterium tuberculosis, still remains a major global health problem. The main obstacle in eradicating this disease is the ability of this pathogen to remain dormant in macrophages, and to get reactivated later under immuno-compromised conditions. The physiology of hypoxic...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2015-06-01 | PXD001158 | Pride
Lc-msms Mycobacterium tuberculosis Dormancy Reactivation Quantitative proteomics 
UnknownPotential of Y. lipolytica epoxide hydrolase for efficient production of enantiopure (R)-1,2-octanediol.
Not available
S-EPMC10371975 | biostudies-literature
UnknownInvestigating ripple pattern formation and damage profiles in Si and Ge induced by 100 keV Ar+ ion beam: a comparative study.
Not available
S-EPMC10999981 | biostudies-literature
UnknownTowards Defining Heterotic Gene Pools in Pearl Millet [Pennisetum glaucum (L.) R. Br.].
Not available
S-EPMC5841052 | biostudies-literature
UnknownPERK regulates skeletal muscle mass and contractile function in adult mice.
Not available
S-EPMC6338633 | biostudies-literature
TranscriptomicsA genome-wide perspective of miRNAome in response to high temperature, salinity and drought stresses in Brassica juncea (Czern) L.
Purpose: To identify high temperature, sailinity and drought-responsive miRNAs at genome wide level in B. juncea var varuna. Results: In this study four small RNA libraries viz. B. juncea control (BJC), B. juncea high temperature stressed (BJH), B. juncea salinity stressed (BJS) and B. juncea drough...
ORGANISM(S): Brassica juncea 
2014-08-20 | E-GEOD-53242 | biostudies-arrayexpress
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