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ProteomicsProteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion
Proteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion
ORGANISM(S): Homo sapiens (Human) 
2025-08-16 | PXD059889 | Pride
Ribonucleoprotein granule Aspscr1 Ubxd9 Tug Protein homeostasis Viscoelasticity Aspl Stress granule Rheology Vcp/p97 G3bp Ulk Multisystem proteinopathy 
TranscriptomicsMito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice
Somatic mitochondrial DNA (mtDNA) mutations contribute to the pathogenesis of age-related disorders, including myelodysplastic syndromes (MDS). The accumulation of mitochondria harboring mtDNA mutations in patients with these disorders suggests a failure of normal mitochondrial quality-control syste...
ORGANISM(S): Mus musculus 
2015-04-21 | E-GEOD-57761 | biostudies-arrayexpress
TranscriptomicsIntegrated Genetic and Epigenetic Analysis of Childhood ALL Reveals a Synergistic Role for Structural and Epigenetic Lesions In Determining Disease Phenotype [194 samples]
Acute lymphoblastic leukemia (ALL), the commonest childhood malignancy, is characterized by recurring gross and submicroscopic structural genetic alterations that contribute to leukemogenesis. Disordered epigenetic regulation is a hallmark of many tumors, and while analysis of DNA methylation of lim...
ORGANISM(S): Homo sapiens 
2013-06-27 | E-GEOD-44860 | biostudies-arrayexpress
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