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GenomicsThe enhancer and promoter landscape of human regulatory and conventional T cell subpopulations
CD4+CD25+FOXP3+ human regulatory T cells (Treg) are essential for self-tolerance and immune homeostasis. Here, we generated genome-wide maps of poised and active enhancer elements marked by histone H3 lysine 4 monomethylation and histone H3 lysine 27 acetylation for CD4+CD25highCD45RA+ naive and CD4...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-43119 | biostudies-arrayexpress
UnknownProspective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand.
Not available
S-EPMC5111628 | biostudies-literature
MetabolomicsStable Isotope-Assisted Metabolomics for Deciphering Xenobiotic Metabolism in Mammalian Cell Culture
Xenobiotics are ubiquitous in the environment and modified abundantly in the human body by phase I and II metabolism. Liquid chromatography coupled to high resolution mass spectrometry is a powerful tool to investigate these biotransformation products. Here, we present a workflow based on stable iso...
2020-04-14 | MTBLS1358 | MetaboLights
UnknownVaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.
Not available
S-EPMC4136246 | biostudies-literature
UnknownOpioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.
Not available
S-EPMC6583638 | biostudies-literature
UnknownIntratumoral Genetic and Functional Heterogeneity in Pediatric Glioblastoma.
Not available
S-EPMC7282886 | biostudies-literature
Genomics3a29872b-a736-415c-b42b-d2ee95d79c54 - samples
WGS with linked reads of pediatric glioblastoma. For each patient, blood and tumor tissue were sequenced. For two patients, we also provide sequencing data for the blood of their parents.
EGAD00001005212 | EGA
GenomicsWhole genome sequencing with linked reads of pediatric glioblastoma samples
Pediatric glioblastoma (pGBM) is a lethal cancer with no effective therapies. To understand mechanisms of tumor evolution in this cancer, we performed whole genome sequencing with linked reads on longitudinally resected pGBM samples. Our analyses showed that all diagnostic and recurrent samples were...
EGAS00001003432 | EGA
GenomicsCharbonneau Cancer Institute DAC
Data Access Committee EGAC00001001280
EGAC00001001280 | EGA
TranscriptomicsGene expression analysis of in vivo-grown tumors treated with compounds that either de-bulk the tumor or target cancer stem cells
A large body of evidence has demonstrated that many human tumors are maintained by a small cell population called cancer stem cells (CSCs) or tumor progenitors, which are responsible for tumor formation, therapy resistance and metastasis. We found that ionizing radiation treatment enriches for the C...
ORGANISM(S): Homo sapiens 
2015-01-23 | E-GEOD-49232 | biostudies-arrayexpress
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