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TranscriptomicsGlobal Changes following N-deprivation in Chlamydomonas: 454 sequencing
Chlamydomonas reinhardtii forms lipid droplets rich in triacylglycerols when nutrient-deprived. To begin studying the mechanisms underlying this process, N-deprivation was used to induce triacylglycerol accumulation and changes in developmental programs such as gametogenesis. Comparative global anal...
ORGANISM(S): Chlamydomonas reinhardtii 
2010-09-24 | E-GEOD-24366 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Chlamydomonas reinhardtii response to nitrogen deprivation
Chlamydomonas reinhardtii forms lipid droplets rich in triacylglycerols when nutrient-deprived. To begin studying the mechanisms underlying this process, N-deprivation was used to induce triacylglycerol accumulation and changes in developmental programs such as gametogenesis. Comparative global anal...
ORGANISM(S): Chlamydomonas reinhardtii 
2010-09-24 | E-GEOD-24365 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver in conditional knockouts of the tumor suppressor gene Apc identifies Wnt/bet-catenin signaling activation in hepatocytes
A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Conditional Knockout mouse model for the tumor suppressor gene Ap, Apc 2lox. The disruption of the Apc gene is realized by injection of an adenovirus encoding the Cre recom...
ORGANISM(S): Mus musculus 
2006-03-13 | E-TABM-81 | biostudies-arrayexpress
TranscriptomicsExpression profiling of mouse liver after treatment with Vascular Endothelial Growth Factor (VEGF) inhibitor aflibercept
Transcriptional profiling of mouse liver was compared between VEGF inhibitor aflibercept and control treatment after 9 weeks. 8-10 week-old SCID mice received VEGF Trap protein (aflibercept) subcutaneously twice per week at 25mg per kg body weight for 9 weeks. For control groups, mice were treated...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-50519 | biostudies-arrayexpress
TranscriptomicsR.palustris: cbbT1 overexpression and cbbT2 overexpression
Transcriptional profiling of Rhodopseudomonas palustris (R. palustris) comparing cbbT1 over-expressing strain with cbbT2 over-expressing strain. Goal was to discriminate the molecular mechanisms between transketolase I (cbbT1) and transketolase II (cbbT2). R.palustris is a purple non-sulfur anoxygen...
ORGANISM(S): Rhodopseudomonas palustris 
2014-05-06 | E-GEOD-29310 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling of intestinal epithelial cells from paediatric biopsies including Inflammatory Bowel disease and healthy controls
We purified the intestinal epithelial cells from biopsies taken from the ileum and colon of a paediatric cohort of IBD patients and healthy controls
ORGANISM(S): Homo sapiens 
2017-10-20 | E-MTAB-5463 | biostudies-arrayexpress
TranscriptomicsRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
In order to unravel the impact of intestinal smooth muscle tissue on the intestinal epithelium, we isolated clean smooth muscle, cultured it for 24h in DMEM-F12, and collected the supernatant (muscle-SN). This supernatant was used to treat small intestinal organoids (made of intestinal epithelium), ...
ORGANISM(S): Mus musculus 
2021-09-27 | E-MTAB-9181 | biostudies-arrayexpress
TranscriptomicsMHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses
Intestinal organoids stimulated with conditioned media from inflamed or non-inflamed source.
ORGANISM(S): Mus musculus 
2023-11-09 | E-MTAB-12414 | biostudies-arrayexpress
TranscriptomicsGlobal Changes following N-deprivation in Chlamydomonas
This SuperSeries is composed of the following subset Series: GSE24365: Global Changes following N-deprivation in Chlamydomonas: Illumina sequencing GSE24366: Global Changes following N-deprivation in Chlamydomonas: 454 sequencing Refer to individual Series
ORGANISM(S): Chlamydomonas reinhardtii 
2010-09-24 | E-GEOD-24367 | biostudies-arrayexpress
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
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