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UnknownCardiovascular Safety of Anagrelide Hydrochloride versus Hydroxyurea in Essential Thrombocythaemia.
Not available
S-EPMC7847982 | biostudies-literature
UnknownPomalidomide is active in the treatment of anemia associated with myelofibrosis.
Not available
S-EPMC4979191 | biostudies-literature
ProteomicsHuman colon organoids reveal distinct physiologic and oncogenic Wnt responses
Constitutive Wnt activation upon loss of Adenoma polyposis coli (APC) acts as main driver of colorectal cancers (CRC). Targeting Wnt signaling has proven difficult because the pathway is crucial for homeostasis and stem cell renewal. To distinguish oncogenic from physiologic Wnt activity, we have pe...
ORGANISM(S): Homo sapiens (Human) 
2019-02-28 | PXD012650 | Pride
Human colon Isogenic lines Organoids Label free quantification Crispr/cas9 Wnt signaling Apc mutation 
UnknownA vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors.
Not available
S-EPMC9918448 | biostudies-literature
ProteomicsATLANTIC: Activity landscapes of tumor cell lines determine drug responses
Analysis of cancer cell line (CCL) genomes, proteomes and phenotypic drug responses are emerging approaches to uncover molecular mechanisms of drug action. We extended this paradigm to measuring proteome activity landscapes by integrating quantitative data for 10,000 proteins and 55,000 phosphorylat...
ORGANISM(S): Homo sapiens (Human) 
2020-07-27 | PXD013615 | Pride
Crc65 Pharmacoproteomics Nci60 Drug sensitivity Tumor cell lines 
UnknownSpecific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia.
Not available
S-EPMC7387317 | biostudies-literature
UnknownProteome activity landscapes of tumor cell lines determine drug responses.
Not available
S-EPMC7371697 | biostudies-literature
UnknownBiomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures.
Not available
S-EPMC11260584 | biostudies-literature
UnknownAnagrelide compared with hydroxyurea in WHO-classified essential thrombocythemia: the ANAHYDRET Study, a randomized controlled trial.
Not available
S-EPMC3591796 | biostudies-literature
UnknownTransglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53.
Not available
S-EPMC8225513 | biostudies-literature
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