Sort   by:  
 Page size 
ProteomicsATLANTIC: Activity landscapes of tumor cell lines determine drug responses
Analysis of cancer cell line (CCL) genomes, proteomes and phenotypic drug responses are emerging approaches to uncover molecular mechanisms of drug action. We extended this paradigm to measuring proteome activity landscapes by integrating quantitative data for 10,000 proteins and 55,000 phosphorylat...
ORGANISM(S): Homo sapiens (Human) 
2020-07-27 | PXD013615 | Pride
Crc65 Pharmacoproteomics Nci60 Drug sensitivity Tumor cell lines 
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Kinobeads
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo sapiens (Human) 
2017-12-12 | PXD005355 | Pride
Personalised medicine Integrated full proteome subtypes Crc65 Mass spectrometry Correlation of mrna and protein abundance Patient stratification Consensus molecular subtypes Cptac Quasar2 Kinobeads 
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo sapiens (Human) 
2017-12-12 | PXD005354 | Pride
Personalised medicine Integrated full proteome subtypes Crc65 Mass spectrometry Correlation of mrna and protein abundance Patient stratification Consensus molecular subtypes Cptac Quasar2 Kinobeads 
UnknownTherapeutic Vulnerability to ATR Inhibition in Concurrent NF1 and ATRX-Deficient/ALT-Positive High-Grade Solid Tumors.
Not available
S-EPMC9221513 | biostudies-literature
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Kinobeads
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081735 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081738 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CPTAC Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo sapiens (Human) 
2017-12-13 | PXD005353 | Pride
Personalised medicine Integrated full proteome subtypes Crc65 Mass spectrometry Correlation of mrna and protein abundance Patient stratification Consensus molecular subtypes Cptac Quasar2 Kinobeads 
Sort   by:  
 Page size