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TranscriptomicsComparison of hypoxia (4 % O2) cultured human embryonic stem cells (hESCs) to normoxia (21 % O2) cultured
We compared the transcriptome at gene expression level in hypoxic and normoxic conditions. The transcriptome of cells cultured at three different timepoints, 2h, 24 h and 7 days with three different cell lines in normoxia and hypoxia was compared 18 samples total, 3 replicates in each conditions, 2h...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-35819 | biostudies-arrayexpress
UnknownAssociation of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population.
Not available
S-EPMC8176385 | biostudies-literature
UnknownCardiac repolarization during fingolimod treatment in patients with relapsing-remitting multiple sclerosis.
Not available
S-EPMC5822581 | biostudies-literature
GenomicsGenome wide promoter methylation analysis of mouse macrophages and endothelial cells isolated from ischemic hindlimbs using RRBS sequencing
Purpose: The goal of this study was to compare the genome-wide promoter methylation alterations in macrophages and endothelial cells during hindlimb ischemia among normal, hyperlipidemic and type-2 diabetic mice. Methods: Unilateral hindlimb ischemia was induced by ligating femoral artery proximal t...
ORGANISM(S): Mus musculus 
2015-12-21 | E-GEOD-65759 | biostudies-arrayexpress
TranscriptomicsAnalysis of HSF2 target genes using a global promoter ChIP-chip strategy on mouse wild-type testis
Mapping of in vivo targets for HSF2 by using mammalian tissue material in a global ChIP-chip promoter screen. Chromatin was isolated from three wild-type (WT) mouse testes, crosslinked and sonicated into fragments of 100-500 bp, and the quality of the DNA was controlled before the immunoprecipitatio...
ORGANISM(S): Mus musculus 
2008-08-05 | E-GEOD-9289 | biostudies-arrayexpress
UnknownEPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis.
Not available
S-EPMC1513590 | biostudies-literature
TranscriptomicsPreprocessed reduced representation bisulfite sequencing (RRBS) data from 173 human umbilical cord blood samples, collected for a study on associations between perinatal DNA methylation marks and progression to type 1 diabetes by age 15
The samples were collected from the participants of the Finnish Diabetes Prediction and Prevention (DIPP) Study, born between 1995 and 2006. DIPP is a prospective follow-up cohort of children with a moderate or high risk of type 1 diabetes, based on the HLA-DR-DQ genotype. Islet cell autoantibodies ...
ORGANISM(S): Homo sapiens 
2022-06-06 | E-MTAB-10530 | biostudies-arrayexpress
TranscriptomicsHSF1 regulates transcription of sex-chromosomal multicopy genes during post-meiotic repression
Mapping of in vivo targets for HSF1 by using mammalian tissue material in a global ChIP-chip promoter screen. Chromatin was isolated from three wild-type (WT) mouse testes, crosslinked and sonicated into fragments of 100-500 bp, and the quality of the DNA was controlled before the immunoprecipitatio...
ORGANISM(S): Mus musculus 
2010-08-31 | E-GEOD-22492 | biostudies-arrayexpress
UnknownDifferential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid.
Not available
S-EPMC1774427 | biostudies-literature
TranscriptomicsGene expression in Drosophila montana
We created a custom-made microarray for D. montana with 101 genes known to affect traits important in diapause, photoperiodism, reproductive behaviour, circadian clock and stress tolerance in model Drosophila species. This array gave us a chance to filter out genes showing expression changes during ...
ORGANISM(S): Drosophila montana 
2010-05-06 | E-GEOD-18475 | biostudies-arrayexpress
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