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TranscriptomicsTranscript profiling of Lymphangioleiomyomatosis (LAM) nodules in Human Patients
Lymphangioleiomyomatosis (LAM) is characterized by cystic lung destruction caused by smooth, muscle-like LAM cells which have mutations in the tumor suppressor genes Tuberous Sclerosis Complex (TSC) 1 or 2, and the capacity to metastasize. Since chemokines and their receptors function in chemotaxis ...
ORGANISM(S): Homo sapiens 
2008-12-30 | E-GEOD-12027 | biostudies-arrayexpress
UnknownETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells.
Not available
S-EPMC8860090 | biostudies-literature
TranscriptomicsTranscription profiling of liver, lung, spleen and kidney from young (13 week) and aged (130 week) wild type mice
We compared the complete mouse liver, spleen, lung and kidney transcriptome of adult 13- and 130-wk old wt C57Bl/6J mice (n=3) to develop gene sets for young adult and aged wt mice, respectively
ORGANISM(S): Mus musculus 
2008-06-01 | E-MEXP-1504 | biostudies-arrayexpress
UnknownComparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry.
Not available
S-EPMC9054878 | biostudies-literature
TranscriptomicsNormal Lung + Lung adenocarcinoma microarray
Gene transcription in a set of 49 human primary lung adenocarcinomas and 9 normal lung tissue samples was examined using Affymetrix GeneChip technology. We aimed to investigate differential gene expression between the two tissue types. A total of 3,442 genes, called the set MAD, were found to be eit...
ORGANISM(S): Homo sapiens 
2005-12-31 | E-MEXP-231 | biostudies-arrayexpress
UnknownThe complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms.
Not available
S-EPMC5503512 | biostudies-literature
TranscriptomicsTranscription profiling of skeletal muscle from wild type and mdx mice at three time points
In this study, in order to minimize the genetic variability of muscle samples we have used two approaches. First, we have analyzed the gene expression profile from a single skeletal muscle, the medial gastrocnemius (MG), and not from a pool of different muscles which could have different expression ...
ORGANISM(S): Mus musculus 
2009-04-16 | E-MEXP-1623 | biostudies-arrayexpress
TranscriptomicsImatinib targeting of KIT-mutant oncoprotein in melanoma
Metastatic melanoma is an aggressive treatment-refractory malignancy. Recently, c-Kit mutations were discovered in certain mucosal melanomas. A clinical trial was initiated with the c-Kit inhibitor imatinib mesylate. The first treated patient experienced dramatic clinical improvement within days, f...
ORGANISM(S): Homo sapiens 
2008-12-23 | E-GEOD-8164 | biostudies-arrayexpress
TranscriptomicsmiR-122 as a Regulator of Mitochondrial Metabolic Gene Network in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, reflecting the need for a better understanding of hepatocarcinogenesis. In this study, we examined the genome-wide expression profiles of both miRNAs and mRNAs from paired tumor and adjacent non-tumor tissues fro...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-22058 | biostudies-arrayexpress
UnknownIdentification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.
Not available
S-EPMC5710474 | biostudies-literature
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