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ProteomicsHuman lamin B1: stress-induced phosphorylation
This is a small scale study of the phosphorylation state of human lamin B1 immunoprecipitated from control cells or cells treated with methyl methane sulphonate (MMS, acting as a DNA damage stressor agent)
ORGANISM(S): Homo sapiens (Human) 
2017-05-30 | PXD006459 | Pride
Human Post translational modification Nuclear envelope Lamin 
GenomicsRedistribution of the Lamin B1 genomic binding profile affects spatial rearrangement of heterochromatic domains and gene expression during senescence
Senescence is a stress responsive form of stable cell cycle exit. Senescent cells have a distinct gene expression profile, which is often accompanied by the spatial redistribution of heterochromatin into senescence-associated heterochromatic foci (SAHFs). Studying a key component of the nuclear lami...
ORGANISM(S): Homo sapiens 
2013-08-22 | E-GEOD-49341 | biostudies-arrayexpress
ProteomicsLamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair
Emerging evidence points to post translational modification (PTM) of nuclear lamins as a key regulator of their diverse roles in nuclear organization, chromatin stability, DNA repair, and cell cycle progression. However, the functions of many of these PTMs remain uncharacterized. Here, we demonstrat...
ORGANISM(S): Homo sapiens (Human) 
2021-01-08 | PXD022974 | Pride
Lamin b1 Acetylation Dna repair Turboid Lamin Nonhomologous end joining 
GenomicsLamin B1 ChIPseq experiments from ER:RAS IMR90s
Lamin B1 from OIS IMR90s We used ChIP-seq to examine the global binding of Lamin B1 in human IMR90 oncogene-induced senescence
ORGANISM(S): Homo sapiens 
2014-12-15 | E-GEOD-53331 | biostudies-arrayexpress
GenomicsLamin B1 dependent transcriptional control in neural progenitor cells
Lamin B1 dependent transcriptional control in neural progenitor cells
PRJNA656852 | ENA
TranscriptomicsTranscription profiling of mouse wild type cells vs Lmnb1 knockout cells
Comparison of gene expression profiles in wild type cells vs Lmnb1 knockout cells.
ORGANISM(S): Mus musculus 
2007-01-08 | E-MEXP-538 | biostudies-arrayexpress
ProteomicsSETD2 N-terminus mediates interaction with Lamins
Histone-Lysine N-methyltransferase SETD2 is an evolutionarily conserved histone methyltransferase that associates with RNA Polymerase II (RNAPII) and catalyzes trimethylation of histone H3 lysine 36 (H3K36me3) in transcribed regions. Interestingly, SETD2 is frequently mutated in cancers. Clear cell ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-04 | PXD040771 | Pride
Setd2 Cdk1 Mitosis Lamin 
GenomicsHuntington’s disease as a lamin B1 nuclear envelopathy
Huntington’s disease as a lamin B1 nuclear envelopathy
PRJNA587460 | ENA
GenomicsMatrix Stiffness Induces Midnolin-dependent Lamin B1 Degradation to Control Myoblast Differentiation
Matrix Stiffness Induces Midnolin-dependent Lamin B1 Degradation to Control Myoblast Differentiation
PRJNA1432657 | ENA
TranscriptomicsLamin binding profiles in the ENCODE regions
A systems understanding of nuclear organization and events is critical for determining how cells divide, differentiate and respond to stimuli and for identifying the causes of diseases. Chromatin remodeling complexes such as SWI/SNF have been implicated in a wide variety of cellular processes includ...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-24382 | biostudies-arrayexpress
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