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To uncover genes regulated by mTORC1 and estradiol in uterine Tsc2-null LAM like cells, we performed RNAseq on uteri from 12-week old wild-type (WT) and uterine-specific Tsc2-null (KO) mice that were either untreated (intact), oopherectomized (ovx) or oopherectomized + treated with 17β-estradiol pe...
ORGANISM(S): Mus musculus 
Shiga toxin type 2 (Stx2) is the main virulence factor produced by Stx-producing Escherichia coli (STEC) responsible for hemorrhagic colitis and the life-threatening sequela hemolytic uremic syndrome.
ORGANISM(S): Homo Sapiens 
2022-11-21 | PXD038256 |
Half of all human transcription factors use C2H2 zinc finger domains to specify site-specific DNA binding and yet very little is known about their role in gene regulation. Based on in vitro studies, a zinc finger code has been developed that predicts a binding motif for a particular zinc finger fact...
ORGANISM(S): Homo sapiens 

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
This study aims to investigate the effects of SBA on the cell cycle, apoptosis, and to verify the mechanism of SBA anti-nutritional characters based on proteomic-based analysis. The IPEC-J2 cell line was cultured with medium containing 0.0, 0.5 or 2.0 mg/mL SBA. With increasing SBA levels, the perce...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Olea europaea (Common olive) Helicobacter pylori J99 (Campylobacter pylori J99) Acyrthosiphon pisum (Pea aphid) Sus scrofa domesticus (domestic pig) Dictyostelium discoideum (Slime mold) Merluccius bilinearis (Silver hake) Rattus rattus (Black rat) Homo sapiens (Human) Mesocricetus auratus (Golden hamster) Brassica oleracea var. botrytis (Cauliflower) Halobacterium salinarum Hepatitis C virus subtype 1a Rattus norvegicus (Rat) Enterococcus faecalis (Streptococcus faecalis) Arabidopsis thaliana (Mouse-ear cress) Arachis hypogaea (Peanut) Cercopithecus aethiops (Green monkey) (Grivet) Nicotiana tabacum (Common tobacco) Gallus gallus (Chicken) Oryza sativa (Rice) Drosophila melanogaster (Fruit fly) Caenorhabditis elegans Bos taurus (Bovine) Solanum tuberosum (Potato) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) Yarrowia lipolytica (Candida lipolytica) Struthio camelus (Ostrich) Pisum sativum (Garden pea) Mus musculus (Mouse) Vigna mungo (Rice bean) (Black gram) Apis mellifera (Honeybee) Pongo pygmaeus (Bornean orangutan) Cicer arietinum (Chickpea) (Garbanzo) Candida albicans (Yeast) Zea mays (Maize) Gadus morhua (Atlantic cod) Bombyx mori (Silk moth) Taeniopygia guttata (Zebra finch) (Poephila guttata) Pan troglodytes (Chimpanzee) Trypanosoma brucei Pinus radiata (Monterey pine) Hordeum vulgare (Barley) Heliocidaris erythrogramma (Sea urchin) Ictalurus punctatus (Channel catfish) Vitis vinifera (Grape) Ricinus communis Triticum aestivum (Wheat) Xenopus laevis (African clawed frog) Brassica napus (Rape) Macaca mulatta (Rhesus macaque) Staphylococcus aureus Equus caballus (Horse) 
2021-05-04 | PXD025751 | Pride

The Office of Cancer Genomics at the National Cancer Institute is sponsoring a series of studies as part of the Cancer Genome Characterization Initiative (CGCI) to assess novel emerging sequencing technologies in cancer. The CGCI program includes comprehensive characterization of the genetic a...

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