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ProteomicsUreter proteomics analysis following stent placement and removal in a porcine model
Symptoms including pain and discomfort commonly present during ureteral stenting is not well understood. We investigated global changes in ureters at the transcriptional, translational, and functional levels while stents are indwelling and following removal and recovery using a porcine model. Polar...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-05-10 | PXD038161 | Pride
Proteomics Tmt Lc-ms Porcine Ureter Stent 
TranscriptomicsGut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids
Acetate, propionate and butyrate are the main short-chain fatty acids (SCFAs) that arise from the fermentation of fibers by the colonic microbiota. While many studies focus on the regulatory role of SCFAs, their quantitative role as a catabolic or anabolic substrate for the host has received relativ...
ORGANISM(S): Mus musculus 
2013-10-21 | E-GEOD-45926 | biostudies-arrayexpress
TranscriptomicsPupylated proteins in Corynebacterium glutamicum revealed by MudPIT analysis
In a manner similar to ubiquitin, the prokaryotic ubiquitin-like protein (Pup) has been shown to target proteins for degradation via the proteasome in mycobacteria. However, not all actinobacteria possessing the Pup protein also harbor a proteasome, suggesting fates for pupylated proteins other than...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2014-06-24 | E-GEOD-48038 | biostudies-arrayexpress
TranscriptomicsH3K64me3 and H3K9me3 profiling at promoters in mouse embryonic stem cells
Histone modifications are central to the regulation of all DNA-dependent processes but the repertoire of known modifications is far from complete. Lysine 64 of Histone H3 (H3K64) lies within the globular domain of H3 at a structurally important position within the nucleosome. We identify tri-methyla...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-16185 | biostudies-arrayexpress
GenomicsDissection of the molecular complexity of colorectal cancer in pre-clinical models identifies predictive signatures of sensitivity to EGFR inhibitors
Colorectal carcinoma (CRC) is a heterogeneous tumour entity, with only a fraction of the tumours responding to currently available therapies. A detailed understanding of the biology and genetics of CRC is a prerequisite for precision medicine. To address this challenge in clinical oncology, the Onco...
EGAS00001001752 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:01:24:124-96 - samples
RNAseq on Illumina HiSeq2000/2500 of WNT reporter of PDO culture derived from colorectal cancer metastasis sample
EGAD00001002074 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:08:19:631-106 - samples
Whole-genome sequencing on Illumina HiSeq2000/2500 of colorectal cancer metastasis sample
EGAD00001002084 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:21:37:629-120 - samples
Whole-exome sequencing on Illumina HiSeq2000/2500 of Patient-derived xenograft derived from colorectal cancer metastasis sample
EGAD00001002098 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:25:47:437-127 - samples
Whole-exome sequencing on AB 5500xl Genetic Analyzer of colorectal cancer metastasis sample
EGAD00001002105 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:10:37:045-110 - samples
Whole-genome sequencing on Illumina HiSeq2000/2500 of colorectal cancer primary tumor sample
EGAD00001002088 | EGA
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