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ProteomicsNCAM1: A Novel Autoantigen in Membranous Lupus Nephritis
Membranous lupus nephritis is a frequent cause of nephrotic syndrome in patients with systemic lupus erythematosus. Unlike phospholipase A2 receptor or thrombospondin type 1 domain containing 7A-associated membranous nephropathy, where known antibodies can be detected within sera by indirect immun...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD021123 | Pride
Human Kidney Dda 
ProteomicsTransforming growth factor receptor beta 3 (TGFBR3)-associated membranous nephropathy
We utilized mass spectrometry for protein discovery through enrichment of glomerular proteins by laser capture microdissection and through elution of immune complexes within MLN biopsies.
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD026506 | Pride
Pulldown Lcmd Lcms Kidney 
ProteomicsMinor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
Background: Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-based proteomics. However, the antigenic targets of disease are unknown for >10% of MN and >50% of membranous lupus nephritis (MLN) cases. We identified multiple new targets in PLA2R-/THSD7A-/EXT-/NELL1-q...
ORGANISM(S): Homo sapiens (Human) 
2023-04-06 | PXD035854 | Pride
Human Kidney Pulldown Membranous nephropathy Dda 
ProteomicsCubilin is a Novel Target Antigen in Anti-Brush Border Antibody Disease
Autoimmune diseases that affect the kidney proximal tubule (PT) cause proteinuria and are implicated in the pathogenesis of kidney failure. Previous evidence demonstrated that circulating anti-brush border antibodies (ABBA) target megalin (LRP2) but whether other components of the PT drive autoimmun...
ORGANISM(S): Homo sapiens (Human) 
2023-04-06 | PXD030159 | Pride
Human Dia Kidney Lc-ms 
UnknownClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Not available
S-EPMC6193486 | biostudies-literature
UnknownAggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
Not available
S-EPMC3971471 | biostudies-literature
UnknownFrequency, Risk Factors, and Outcome of Coexistent Small Vessel Disease and Intracranial Arterial Stenosis: Results From the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) Trial.
Not available
S-EPMC5714507 | biostudies-literature
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