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TranscriptomicsLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Determining the spatial and temporal expression of genes involved in the ovulatory pathway is critical for the understanding of the role of each estrogen receptor in the modulation of folliculogenesis and ovulation. Estrogen receptor (ER) b is highly expressed in ovarian granulosa cells and mice lac...
ORGANISM(S): Mus musculus 
2013-07-03 | E-GEOD-44651 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Citrus clementina laser microdissected epidermis and subepidermis from expanding green fruit rind
Transcriptomic profiling of laser microdissected epidermis and subepidermis cells from expanding green fruit rind of Citrus clemenules using the cDNA microarray CFGP-Citrus_20k.
ORGANISM(S): Citrus clementina 
2010-05-23 | E-TABM-954 | biostudies-arrayexpress
ProteomicsPAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples
Aberrations in histone post-translational modifications (hPTMs) have been linked with various pathologies, including cancer, and could represent not only useful biomarkers, but also suggest possible targetable epigenetic mechanisms. We have recently developed an approach, termed pathology tissue ana...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-07-17 | PXD006027 | Pride
Laser microdissection Epigenetic marker Histone post-translational modifications Proteomics Mass spectrometry Pat-h-ms Formalin-fixed paraffin embedded 
TranscriptomicsMouse sinoatrial node transcriptome
RNA Sequencing of Mouse Sinoatrial Node Reveals an Upstream Regulatory Role for Islet-1 in Cardiac Pacemaker Cells Rationale: Treatment of sinus node disease with regenerative or cell-based therapies will require a detailed understanding of gene regulatory networks in cardiac pacemaker cells (PCs)....
ORGANISM(S): Mus musculus 
2015-02-06 | E-GEOD-65658 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of components isolated from developing kidney at E11.5, E12.5 & E15.5 using LCM. (GUDMAP Series ID: 10)
The long term objective is to create an encyclopedia of the expression levels of all genes in multiple components of the developing kidney. The central thesis is straightforward. The combination of laser capture microdissection (LCM) plus microarray analysis offers a powerful, efficient and effecti...
ORGANISM(S): Mus musculus 
2006-11-18 | E-GEOD-6290 | biostudies-arrayexpress
TranscriptomicsThe transitional Gene Expression Profiling of Ovarian Follicle Treated with Indomethacin and RU486 in Rats
Indomethacin (an inhibitor of prostaglandin synthesis) and RU486 (mifepristone, progesterone receptor antagonist) are well known compounds which impair follicle rupture in rats, nevertheless the histopahotlogical figures of these follicle were different in detail due to the difference of the pathway...
ORGANISM(S): Rattus norvegicus 
2014-02-01 | E-GEOD-54584 | biostudies-arrayexpress
TranscriptomicsAbscission layer (AL) at the base of flower in rice using laser micro-dissection: NIL(qSH1) AL vs. Nipponbare AL, NIL(qSH1) AL vs. NIL(qSH1) upper region of AL, and NIL(qSH1) AL vs. NIL(qSH1) lower region of AL
Tissue-specific transcriptional profiling of the abscission layer (AL) at the base of young flower in rice using laser micro-dissection: NIL(qSH1) vs. Nipponbare. We used two rice varieties, NIL(qSH1) and Nipponbare. NIL(qSH1) is a nearly isogenic line containing the seed shattering gene qSH1. Seed ...
ORGANISM(S): Oryza sativa 
2012-03-31 | E-GEOD-33409 | biostudies-arrayexpress
UnknownTissue-based metabolite profiling and qualitative comparison of two species of Achyranthes roots by use of UHPLC-QTOF MS and laser micro-dissection.
Not available
S-EPMC5859166 | biostudies-literature
ProteomicsCell-type resolution proteomics for functional annotation of the grain filling process in wheat endosperm
Grain development is a key life cycle stage of many plants. The development of seeds is the basis of agriculture and the primary source of calories consumed by humans. Here, we employ laser micro dissection (LMD) combined with shotgun proteomics to generate a cell-type proteome atlas of developing w...
ORGANISM(S): Triticum aestivum (Wheat) 
2024-12-11 | PXD035848 | Pride
Proteomics Laser micro dissection (lmd) Starchy endosperm Transfer cells Wheat Sub aleurone Aleurone 
ProteomicsSingle Cell Immuno-laser Microdissection Coupled to Label-free Proteomics to Reveal the Proteotypes of Human Brain Cells After Ischemia
Cerebral ischemia entails rapid tissue damage in the affected brain area causing devastating neurological disorders. The use of biomarkers in stroke might have a major impact in patients’ management, both in the diagnosis and the prognosis. Thus, the analysis of the brain proteome is a straightforwa...
ORGANISM(S): Homo sapiens (Human) 
2017-12-04 | PXD003519 | Pride
Proteomics Label-free Stroke Brain ischemia Laser micro-dissection Biomarker 
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