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TranscriptomicsLaser capture microdissection of endothelial and neuronal cells from human dorsolateral prefrontal cortex
We used laser capture microdissection to isolate both microvascular endothelial cells and neurons from post mortem brain tissue from patients with schizophrenia and bipolar disorder and healthy controls. RNA was isolated from these cell populations, amplified, and analysed using Affymetrix HG133plus...
ORGANISM(S): Homo sapiens 
2008-12-18 | E-GEOD-12679 | biostudies-arrayexpress
TranscriptomicsMelampsora larici-populina gene expression in different tissues of uredinia
Laser Capture Microdissection (LCM) was used for expression analysis of three contrasted fungal tissues of uredinia corresponding respectively to spores and sporogenous hyphae, fungal structures in the spongy mesophyll and fungal infection structures in the palisade mesophyll. The array probes were ...
ORGANISM(S): Melampsora laricis-populina 
2010-07-22 | E-GEOD-21487 | biostudies-arrayexpress
TranscriptomicsTranscriptome of Ameloblastoma using Laser capture microdissection
The goal of the study was to characterize the whole genome transcriptome profiles of pure sample population of human ameloblastoma epithelial cells for examination of molecular pathways. Seventeen human ameloblastoma samples were obtained. Both fresh frozen and FFPE samples were used and placed in s...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-68531 | biostudies-arrayexpress
TranscriptomicsLaser Capture Microdissection and RNA Sequencing Human Adamantinomatous Craniopharyngioma
Laser capture microdissection of cluster cells, palisading epithelium and glial tissue from 2 cases of human adamantinomatous craniopharyngioma. 1 case performed in duplicate.
ORGANISM(S): Homo sapiens 
2018-04-11 | E-MTAB-5266 | biostudies-arrayexpress
TranscriptomicsGene Expression Data from Senescent vs Non-senescent Cells in the in Vivo Human Annulus
The presence of senescent cells in the aging/degenerating human disc is now well-recognized. Senescent cells are viable, cannot divide, remain metabolically active and accumulate within the disc over time. Molecular analysis of senescent cells in tissue, however, offers a special challenge since the...
ORGANISM(S): Homo sapiens 
2009-07-15 | E-GEOD-17077 | biostudies-arrayexpress
TranscriptomicsExpression data from LCM captured prostate cancer cells
The prostate represents a complex mix of cell types and there is a need to analyze distinct cell populations to better understand their potential interactions. This study of cell-type specific gene expression patterns will contribute to understanding of how tumor epithelial cells may be affected by...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-20758 | biostudies-arrayexpress
TranscriptomicsGene Expression in Perivenous Hepatocytes: A Laser Capture Microdissection and Transcriptomic Analysis.
Differential expression of genes and proteins, as well as physiological processes, along the hepatic acinus, known collectively as hepatic zonation, is a fundamental feature of hepatic physiology. However, the precise cellular location of only a relatively small proportion of the ~14,000 genes expre...
ORGANISM(S): Mus musculus 
2013-06-26 | E-GEOD-48273 | biostudies-arrayexpress
ProteomicsLow-melting point agarose as embedding medium for MALDI mass spectrometry imaging and laser-capture microdissection-based proteomics
We report an investigation of low-temperature embedding media in terms of their mechanical properties and embedding temperature, with the goal of determining a reliable embedding medium for the combination of MALDI MSI of lipids, laser-capture microdissection of tissue regions, and quantitative prot...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD045349 | Pride
Proteomics Laser-capture microdissection Maldi msi Embedding media 
TranscriptomicsRNA-Seq Analysis of Laser-Capture Microdissected Cells of the Developing Central Starchy Endosperm of Maize
Endosperm is a product of double fertilization, and provides nutrients and signals to the embryo during seed development in flowering plants. Early stages of endosperm development are critical for the development of its storage capacity through synthesis and accumulation of starch and storage protei...
ORGANISM(S): Zea mays 
2014-06-17 | E-GEOD-58504 | biostudies-arrayexpress
TranscriptomicsLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Determining the spatial and temporal expression of genes involved in the ovulatory pathway is critical for the understanding of the role of each estrogen receptor in the modulation of folliculogenesis and ovulation. Estrogen receptor (ER) b is highly expressed in ovarian granulosa cells and mice lac...
ORGANISM(S): Mus musculus 
2013-07-03 | E-GEOD-44651 | biostudies-arrayexpress
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