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MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
TranscriptomicsTranscription profiling by array of human Acute Lymphobastic Leukemia xenografts in mouse to validate the mouse model
Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms. For haematological malignancies, the non-obese diabetic/severe combined immunodeficient (NOD/SCID) mouse is one of the most successful models to ...
ORGANISM(S): Homo sapiens 
2010-04-26 | E-MEXP-2648 | biostudies-arrayexpress
UnknownVisually Identified Tau 18F-MK6240 PET Patterns in Symptomatic Alzheimer's Disease.
Not available
S-EPMC9484111 | biostudies-literature
TranscriptomicsTranscription profiling of fibroblast-like synovial cells from normal adult horse following treatment with hyaluronan and challenged with lipopolysaccharide
Greater than 95% confluent (Day 0) fibroblast-like synovial cells from the hind limbs (pelvic limb) of normal adult horses were allocated in triplicate to one of 4 groups:

(group 1) unchallenged;
(group 2) LPS-challenged;
(group 3) LPS-challenged following pre-treatment and susta...
ORGANISM(S): Equus caballus 
2007-01-10 | E-MEXP-940 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse AM-14 B cells stimulated through the B cell receptor (BCR) and/or Toll-like receptors (TLR)
We have previously shown that rheumatoid factors (RF) produced by Fas-deficient autoimmune-prone mice typically bind autologous IgG2a with remarkably low affinity. Nevertheless, B cells representative of this RF population proliferate vigorously in response IgG2a/chromatin immune complexes through a...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6674 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human bronchial epithelial cells treated with cigarette smoke and mycobacteria
Exposure to cigarette smoke (CS) is a known risk factor for pulmonary tuberculosis, and smokers are at increased risk of treatment failure and relapse. Using differentiated primary human bronchial epithelial cells (PBEC), we studied whether there is a direct effect of acute CS exposure on epithelial...
ORGANISM(S): Homo sapiens 
2026-07-10 | E-MTAB-17246 | biostudies-arrayexpress
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
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