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TranscriptomicsDNA methylation profiling in primary Diffuse Large B cell Lymphoma (DLBCL) and normal Germinal Center B Cells
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study we carried out genome-wide DNA methylatio...
ORGANISM(S): Homo sapiens 
2014-01-18 | E-GEOD-54200 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of retinae from wildtype and retinoschisin knockout mice (Rs1h-/Y) at postnatal day 7 to understand the effect of retinoschisin on gene expression
Genome-wide expression profiling of the retinoschisin deficient retina in C57CL/6 mice. Experiment Overall Design: RNAs from retinae from 3 Wildtype Mice versus 3 Retinoschisin-KO mice (Rs1h-/Y) at postnatal day 7 (P7) were hybridized onto Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-5581 | biostudies-arrayexpress
TranscriptomicsPRPF8 CLIP seq for iPSC, kidney organoid, retinal organoid, and retinal epithelium derived from c.6926A>C RPE with Retinitis Pigmentosa patients and CRISPR/Cas9 corrected
Retinitis Pigmentosa is a group of inherited eye disorders characterized by progressive degeneration of photoreceptor cells in the retina, leading to vision loss and eventual blindness. One of the known genetic mutations associated with RP is the c.6926A>C mutation in the RPE (retinal pigment epithe...
ORGANISM(S): Homo sapiens 
2024-03-13 | E-MTAB-13171 | biostudies-arrayexpress
TranscriptomicsComparison of two hepatocellular cancer cell lines with distinct properties regarding epithelial-mesenchymal transition
The epithelial to mesenchymal transition (EMT) of malignant hepatocytes is a crucial event in hepatocellular carcinoma (HCC) progression and recurrence. We aimed to establish a human model of EMT to examine drug efficacy and specificity in HCC progression. Human HCC cell populations were characteriz...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-26391 | biostudies-arrayexpress
TranscriptomicsThe PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans
Purpose: Pre-ribosomal RNA is cleaved at defined sites, but many endonucleases involved in 18S rRNA release are not known. We apply an in vivo cross-linking technique coupled with deep sequencing (CRAC) that captures transcriptome-wide interactions between a yeast candidate pre-rRNA endonuclease (Ut...
ORGANISM(S): Saccharomyces cerevisiae 
2016-04-01 | E-GEOD-75991 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Drosophila simulans and Drosophila mauritiana developing male genitalia
We generated RNA-seq data of Drosophila simulans and Drosophila mauritiana developing male genitalia in order to identify expression level differences between these species. These species are closely related, yet have dramatic differences in their male genital morphologies. Three independent RNA...
ORGANISM(S): Drosophila simulans 
2020-08-29 | E-MTAB-9465 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-28-08-2015-09:49:06:632-229 - samples
RNA-sequencing data from teh hT-RPE-MycER cell line after MYC activation and after MINCR knock-down in conditions of MYC ON or OFF
EGAD00001001598 | EGA
TranscriptomicsMolecular profiling of single circulating tumor cells with diagnostic intention
About 230 clinical trials currently explore the role of circulating tumor cell (CTC) analysis for therapy decisions, but no assays enable comprehensive molecular characterization of CTCs with diagnostic precision. We therefore combined a workflow for CTC enrichment and isolation with 100% purity wit...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-58192 | biostudies-arrayexpress
MetabolomicsGNPS - Dataset Creation from GNPS Molcular Networking - 89895d4507c84596a6a01685bfd8acd4
Molecular Networking of fungal culture extracts from T. erinacei analyzed by LC-MS in positive ion mode
ORGANISM(S): Trichophyton Erinacei (ncbitaxon:523106) 
2021-04-29 | MSV000087335 | GNPS
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