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This dataset contains a 4D-DIA proteomic analysis of B16F10 mouse melanoma cells treated with SMT (SM@CMC-KP101). B16F10 cells were divided into two groups: a PBS control group and an SMT treatment group. After drug exposure, cellular proteins were extracted, digested and analyzed by LC-MS/MS using ...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-02 | PXD074961 | Pride
A rat model of skeletal muscle mechanical compression injury was established with varying degrees of injury severity, one control group, and two compression groups (Mild Injury and Severe Injury Group). LC-MS/MS-4D-DIA quantitative proteomics technology was employed to detect the plasma protein expr...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD052469 | Pride
This project aims to identify and quantify TPM3P9 RNA-associated proteins in primary breast cancer cells (PBCs#2/#3/#5) and bone-metastatic breast cancer cells (BMBCs#2/#3/#5) using 4D-DIA LC–MS/MS. RNA pulldown assays were performed with tRSA-based TPM3P9 RNA to capture interacting proteins, which ...
ORGANISM(S): Homo Sapiens 
2025-10-31 | PXD070203 |
We developed a tumor extracellular O-GlcNAcylated proteome identification system, which involving removement of tumor cells by centrifugation, collection of extracellular O-GlcNAcylated proteome by immunoprecipitation using anti-O-GlcNAc antibodies and measurement of data by liquid chromatography-ta...
ORGANISM(S): Homo Sapiens 
This dataset contains lysine lactylation proteomics data generated from G2/M-synchronized sorafenib-resistant HepG2 cells using a 4D DIA LC-MS/MS workflow. Lactylated peptides were enriched and analyzed to characterize lactylation events associated with G2/M. The dataset provides a resource for iden...
ORGANISM(S): Homo Sapiens 
Left ventricular hypertrophy (LVH) is critical in chronic kidney disease (CKD), but its mechanisms remain unclear. This study employed multi-omics approaches, including RNA-seq and integrated metabolomics, to characterize metabolic alterations in cardiomyocytes (CM) of CKD mice, revealing enhanced g...
ORGANISM(S): Homo sapiens (Human) 
2026-09-30 | PXD077955 | Pride
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