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ProteomicsActl7b-deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis
Actin-related proteins (Arp) are classified according to their similarity to actin and are involved in diverse cellular processes. ACTL7B is a testis-specific Arp and highly conserved in rodents and primates. ACTL7B is specifically expressed in round and elongating spermatids during spermiogenesis. ...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-19 | PXD038920 | Pride
Actl7b Lc8 light chains Actin-related proteins Mouse Infertility Spermatogenesis 
UnknownActl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis.
Not available
S-EPMC10652042 | biostudies-literature
TranscriptomicsUV (UVC, 10J/m2) light irradiation effect on Ewing Sarcoma cells
LAP-35 and SK-N_MC cells were treated with 10 J/m2 UV light versus untreated Alternative pre-mRNA processing plays a key role in the response to DNA damage as well as in neoplastic transformation. We found that two Ewing Sarcoma (ES) cell lines exhibit different sensitivity to UV light irradiation, ...
ORGANISM(S): Homo sapiens 
2015-10-20 | E-GEOD-59889 | biostudies-arrayexpress
UnknownDynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels.
Not available
S-EPMC11999606 | biostudies-literature
UnknownLight chain-dependent self-association of dynein intermediate chain.
Not available
S-EPMC3020764 | biostudies-literature
UnknownDynein light intermediate chain in Aspergillus nidulans is essential for the interaction between heavy and intermediate chains.
Not available
S-EPMC2787338 | biostudies-literature
UnknownThe Drosophila LC8 homolog cut up specifies the axonal transport of proteasomes.
Not available
S-EPMC5665441 | biostudies-literature
UnknownStructural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex.
Not available
S-EPMC1885999 | biostudies-literature
TranscriptomicsGene expression changes in primary mouse fibroblasts in the absence of ASCIZ
In order to identify potential transcriptional targets of ASCIZ, we performed a microarray analysis of three wildltype and ASCIZ(ATMIN/ZNF822)-deficient littermate single-passage MEF cultures. Only 22 and 25 genes were found to be down- or upregulated in the KO, respectively, by >1.5-fold (p<0.05)....
ORGANISM(S): Mus musculus 
2011-12-21 | E-GEOD-30417 | biostudies-arrayexpress
UnknownGephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes.
Not available
S-EPMC6758200 | biostudies-literature
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