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ProteomicsProject title: Endogenous AIRE-immunoprecipitation from primary human neutrophils
Autoimmune regulator (AIRE) is a transcriptional regulator. We here assess the role for AIRE in primary human neutrophils. We found that the functional role for AIRE in neutrophils is to regulate the extrinsic apoptotic pathway involving the Fas/TNFR death receptors and Cathepsin G and the expressio...
ORGANISM(S): Homo sapiens (Human) 
2024-01-25 | PXD047989 | Pride
Neutrophil Aire Human 
TranscriptomicsComparative analysis of monocytes from healthy donors, patients with metastatic breast cancer, sepsis or tuberculosis.
Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells, which increase in cancer patients. The molecular mechanism behind their generation and function is unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer, the presence and relevanc...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-65517 | biostudies-arrayexpress
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